Memory Clinical Trial
Official title:
Influence of the Dietary Supplement Luteolin on Memory in Healthy Subjects
Proof of concept study on physiological processes (forgetting and memory functions, attention, working memory) in participants after multiple administration of the dietary supplement Luteolin.
In the experimental phase the investigator will administer 500 mg Luteolin (2x250 mg
capsules) per day formulated for oral administration for 7.5 days (first intake: visit 1/3 in
the morning; last intake: visit 2/4 in the morning). The last intake on visits 2 resp. 4 is
important as the participants then have to recall the learned material from visits 1 resp. 3
during a steady-state status of Luteolin.
Subjects will be randomly allocated to treatment groups (starting with investigational
product or placebo).
Identity of Investigational Product: Luteolin extracted from Chrysanthemum Ramat 98% HPLC by
Scyherb® food grade certified according to Safe Quality Foods (SQF) - Level 3 Comprehensive
Food Safety and Quality Management System Certification by the Safe Quality Food Institute
(SQFI).
Control intervention consists of identical looking placebo capsules containing mannitol
formulated for oral administration to be taken twice daily (e.g. every morning and evening)
for 7.5 days (first intake: visit 1/3 in the morning; last intake: visit 2/4 in the morning)
with water.
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