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Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of Melasma

Melasma Clinical Trial

Official title:
Randomized, Controlled, Double-blind Study of Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of Melasma

Clinical Trial Summary

This study assess the effectiveness of oral tranexamic acid in combination with hydroquinone cream in the treatment of melasma.

Clinical Trial Description

Hydroquinone (HQ) is considered the gold standard depigmenting agent for melasma, nevertheless, many patients are recalcitrant to this treatment.

Recent studies have shown that tranexamic acid, a plasmin inhibitor, can prevent UV-induced pigmentation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03751163
Study type Interventional
Source Fakultas Kedokteran Universitas Indonesia
Contact
Status Completed
Phase Phase 3
Start date March 16, 2016
Completion date April 2, 2017
View Details
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