Study of Light Treatment and Laser Treatment for Melasma

Melasma Clinical Trial

Official title:

A Randomized, Rater-blinded, Split-face Comparison of the Efficacy of Intense Pulse Light vs. Q-switched Nd:Yag Laser for the Treatment of Melasma.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00509977
• Other study ID #: STU706
• Status: Completed
• Phase: N/A
• Start date: April 2007
• Est. completion date: September 2009

Study information

• Verified date: December 2021
• Source: Northwestern University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine the efficacy of light treatment and laser treatment for melasma. These treatment options have not been thoroughly explored in the treatment of melasma. By studying the effect of different treatments, a better treatment plan may be developed for people with melasma.

Description:

The objective of this study is to determine the efficacy of light treatment and laser treatment for melasma. These treatment options have not been thoroughly explored in the treatment of melasma. By studying the effect of different treatments, a better treatment plan may be developed for people with melasma.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 17
• Est. completion date: September 2009
• Est. primary completion date: September 2009
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• Diagnosis of melasma lesion measuring at least 4 square centimeters.

• Age 18-75 years.

• Good health.

• Willingness and ability to understand and provide informed consent for participation in the study.

• Ability to communicate with the investigator.

• Must be willing to forgo other treatment options for melasma during the course of the study.

Exclusion Criteria:

• Inability to understand the protocol or to give informed consent.

• Mental illness.

• Under 18 years of age and over 75 years of age.

• Laser treatment in the last 6 months before enrollment.

• Isotretinoin within the past year.

• Lidocaine allergy.

• History of herpes simplex viral infection.

• Concurrent active disease to facial area (i.e acne).

• Bleeding disorder.

• History of abnormal wound healing.

• History of abnormal scarring.

Related Conditions & MeSH terms

• Melanosis
• Melasma

Intervention

Procedure:
• Light Treatment
Light treatment applied to half of the face at each study visit
• Laser Treatment
Laser treatment applied to half of the face at each study visit

Locations

Country	Name	City	State
United States	Northwestern University Feinberg School of Medicine, Department of Dermatology	Chicago	Illinois

Sponsors (1)

Lead Sponsor	Collaborator
Northwestern University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Melasma Area and Severity Index		20 weeks
Secondary	Safety		20 weeks