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Clinical Trial Summary

This is a phase I/Ib, open label study. The escalation portion will characterize the safety and tolerability of DKY709 and DKY709 in combination with PDR001 in subjects with NSCLC or melanoma who have received prior anti-PD-1/PD-L1 therapy, or subjects with NPC. After the determination of the MTD/RD for a particular treatment arm, dose expansion will further assess safety, tolerability, PK/PD, and anti-tumor activity of each regimen at the MTD/RD.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03891953
Study type Interventional
Source Novartis
Contact
Status Active, not recruiting
Phase Phase 1
Start date May 7, 2019
Completion date September 12, 2024

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