Safety of Intranodal ECI-006 in Melanoma Patients

Status Terminated

Clinical Trial Summary

The purpose of this study is to assess the safety and tolerability of cancer immunotherapy ECI-006 and to determine its ability to induce a measurable immune response against the tumor associated antigens. In Cohort 1, ECI-006 will be administered 5 times by intranodal injection in melanoma patients after resection of their tumor. In Cohort 2, ECI-006 will be administered 9 times by intranodal injection on top of standard of care anti PD1 in metastatic melanoma patients with stable disease after 3 to 12 months treatment. ECI-006 activates key immunologically active cells to direct the immune system against the cancer. Expected potential risks for ECI-006 are non-serious and related to the local administration of the product. Hence, the therapy suggested here has the promise to offer considerable benefit to patients without any major risk.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Melanoma

Clinical Trial Details

NCT number	NCT03394937
Study type	Interventional
Source	eTheRNA immunotherapies
Contact
Status	Terminated
Phase	Phase 1
Start date	June 27, 2017
Completion date	January 29, 2021

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