Melanoma Clinical Trial
Official title:
Multi-centre, Retrospective, Open Label Study, to Establish and Validate ML-PrediCare for Patients of Advanced Melanoma Undergoing Immunotherapy, as a 1st, 2nd and Later Lines
This is a retrospective, open label study to establish and validate a prediction technology for advanced melanoma patients under the 1st, 2nd and later treatment lines, with the immunotherapeutic drugs Ipilimumab, Pembrolizumab & Nivolumab, in order to predict response rate and disease progression
The aim of this project is to develop a technology application (termed ML-PrediCare), which
is meant to be a predictive stand-alone software device, to support clinicians'
decision-making, by predicting the individual patient's response to immunotherapy
treatments, e.g., in terms of time-to-progression (TTP).
In Stage I of the study, data will be collected for establishing a training set and assess
the predictive potential of the modelling technology for the response of melanoma patients
to immunotherapy. In Stage II of the study, data will be collected in order to establish a
validation set and test the predictive power of the modelling technology in an independent
set of patients diagnosed with melanoma.
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Observational Model: Cohort, Time Perspective: Retrospective
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