Melanoma Clinical Trial
Official title:
Treatment of Port Wine Stains in Children With Pulsed Dye Laser and Timolol Gel
Pulsed dye laser (PDL)is the gold standard treatment of port wine stains (PWS). However,
many sessions are required and failure or relapses are not uncommon. It has been
demonstrated that a neoangiogenesis occurs after PDL, explaining at least partially those
failure. The objective of this study is to evaluate the use of a topical beta-blocker
(timolol 1% gel) as a combination treatment with PDL for treating PWS.
Methods. Prospective multicenter study comparing PDL alone to PDL + timolol. Sessions of PDL
will be performed once a month for 3 months. One group will be treated with PDL alone and
the other will also applied timolol 1% gel twice a day during treatment. The evaluation will
be done one month after the third session.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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