Melanoma Clinical Trial
Official title:
Acquisition of Human Gynecologic Specimens to be Used in Studying the Causes, Diagnosis, Prevention and Treatment of Cancer
Verified date | October 2016 |
Source | Gynecologic Oncology Group |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Observational |
This laboratory study is collecting tumor tissue and blood samples from patients with gynecologic tumors. Collecting and storing samples of tumor tissue and blood from patients with cancer to study in the laboratory may help in the study of cancer.
Status | Completed |
Enrollment | 275 |
Est. completion date | |
Est. primary completion date | January 2016 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Any of the following: - Patients who have had gynecologic tissue removed during surgery to diagnosis, treat, monitor, and/or prevent primary, persistent, or recurrent gynecologic cancer of the ovary, peritoneum, fallopian tube, cervix, uterine corpus, vagina, or vulva, meeting at least one of the following criteria: - Group A: Women who underwent surgery, were diagnosed with a primary gynecologic malignancy of the ovary, cervix, uterine corpus, or vulva, and have primary tumor, normal tissue, and blood available for submission for this protocol - Patients with ovarian cancer including all stages, grades, and common epithelial cell types - Invasive cancers and serous and mucinous borderline tumors of low malignant potential are allowed - At least 1 gram of frozen primary tumor tissue must be submitted for this protocol for patients with FIGO stage III or IV epithelial ovarian cancer - Patients with an invasive malignancy of the cervix or uterine corpus including all stages, grades, and common cell types - Patients with squamous cell carcinoma of the vulva - Group B: Women who underwent surgery and were diagnosed with a rare gynecologic malignancy of the ovary, peritoneum, fallopian tube, cervix, uterine corpus, vagina, vulva, a gestational trophoblastic tumor, or a tumor arising in endometriosis, and have tumor tissue available for submission for this protocol - Patients with a rare gynecologic malignancy of the ovary including malignant germ cell tumors; sex cord-stromal tumors; malignant mixed mesodermal tumors; clear cell, mucinous, small cell, or transitional cell carcinomas; malignant Brenner tumors; or borderline tumors of low malignant potential (except serous and mucinous) - Patients with a rare gynecologic malignancy of the peritoneum, including primary peritoneal cancer or mesothelioma - Patients with carcinoma of the fallopian tube - Patients with a rare gynecologic malignancy of the cervix including verrucous, small cell, clear cell, serous, or adenoid cystic carcinomas; carcinoid tumors; malignant mixed mesodermal tumors; or leiomyosarcoma - Patients with a rare gynecologic malignancy of the uterine corpus including leiomyosarcoma; malignant mixed mesodermal tumors; endometrial stromal sarcomas; smooth muscle tumors of unknown malignant potential; or clear cell or small cell carcinomas - Patients with a rare gynecologic malignancy of the vagina including verrucous or clear cell carcinomas; melanoma; embryonal rhabdomyosarcoma; or endodermal sinus tumor - Patients with a rare gynecologic malignancy of the vulva including verrucous carcinoma; melanoma; aggressive angiomyxoma; sarcoma; malignant Paget's disease; or Bartholin gland carcinoma - Patients with a gestational trophoblastic tumor - Patients with a tumor arising in endometriosis - Group C: Women who underwent prophylactic oophorectomy and have at least 1 gram of ovarian tissue and blood available for submission for this protocol - Group D: Women who underwent surgery to monitor or treat a persistent or recurrent gynecologic malignancy of the ovary, peritoneum, fallopian tube, cervix, uterine corpus, vagina, or vulva, and have persistent or recurrent tumor, normal tissue, and blood available for submission for this protocol - Concurrent primary cancers are allowed - No benign cystic tumors of the ovary, including cystic epithelial tumors and mature cystic teratomas - Prior cytotoxic chemotherapy allowed - Prior hormonal therapy allowed - Prior radiotherapy allowed - Prior surgery allowed - No more than 6 weeks after prior surgery |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | Abington Memorial Hospital | Abington | Pennsylvania |
United States | Akron General Medical Center | Akron | Ohio |
United States | University of New Mexico Cancer Center | Albuquerque | New Mexico |
United States | Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania |
United States | The Don and Sybil Harrington Cancer Center | Amarillo | Texas |
United States | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan |
United States | Our Lady Bellefonte Hospital | Ashland | Kentucky |
United States | Northside Hospital | Atlanta | Georgia |
United States | MultiCare Auburn Medical Center | Auburn | Washington |
United States | Augusta University Medical Center | Augusta | Georgia |
United States | Colorado Gynecologic Oncology Group | Aurora | Colorado |
United States | University of Colorado Cancer Center - Anschutz Cancer Pavilion | Aurora | Colorado |
United States | University Medical Center Brackenridge | Austin | Texas |
United States | MedStar Franklin Square Medical Center/Weinberg Cancer Institute | Baltimore | Maryland |
United States | The Union Memorial Hospital | Baltimore | Maryland |
United States | Woman's Hospital | Baton Rouge | Louisiana |
United States | Walter Reed National Military Medical Center | Bethesda | Maryland |
United States | Saint Luke's University Hospital-Bethlehem Campus | Bethlehem | Pennsylvania |
United States | Roswell Park Cancer Institute | Buffalo | New York |
United States | Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California |
United States | Cooper Hospital University Medical Center | Camden | New Jersey |
United States | Providence Regional Cancer System-Centralia | Centralia | Washington |
United States | UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina |
United States | Medical University of South Carolina | Charleston | South Carolina |
United States | Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina |
United States | Novant Health Presbyterian Medical Center | Charlotte | North Carolina |
United States | Chattanooga's Program in Women's Oncology | Chattanooga | Tennessee |
United States | Northwestern University | Chicago | Illinois |
United States | Rush University Medical Center | Chicago | Illinois |
United States | University of Illinois | Chicago | Illinois |
United States | Marshfield Clinic-Chippewa Center | Chippewa Falls | Wisconsin |
United States | Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio |
United States | University of Cincinnati | Cincinnati | Ohio |
United States | Case Western Reserve University | Cleveland | Ohio |
United States | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa |
United States | Mercy Cancer Center-West Lakes | Clive | Iowa |
United States | University of Missouri - Ellis Fischel | Columbia | Missouri |
United States | Ohio State University Comprehensive Cancer Center | Columbus | Ohio |
United States | Riverside Methodist Hospital | Columbus | Ohio |
United States | Clements University Hospital | Dallas | Texas |
United States | Parkland Memorial Hospital | Dallas | Texas |
United States | UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas |
United States | Zale Lipshy University Hospital | Dallas | Texas |
United States | Danbury Hospital | Danbury | Connecticut |
United States | Geisinger Medical Center | Danville | Pennsylvania |
United States | Iowa Lutheran Hospital | Des Moines | Iowa |
United States | Iowa Methodist Medical Center | Des Moines | Iowa |
United States | Iowa-Wide Oncology Research Coalition NCORP | Des Moines | Iowa |
United States | Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa |
United States | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa |
United States | Mercy Medical Center - Des Moines | Des Moines | Iowa |
United States | Wayne State University/Karmanos Cancer Institute | Detroit | Michigan |
United States | Marshfield Clinic Cancer Center at Sacred Heart | Eau Claire | Wisconsin |
United States | Sacred Heart Hospital | Eau Claire | Wisconsin |
United States | Saint Elizabeth Medical Center South | Edgewood | Kentucky |
United States | Highlands Oncology Group PA - Fayetteville | Fayetteville | Arkansas |
United States | Washington Regional Medical Center - Fayetteville | Fayetteville | Arkansas |
United States | Saint Francis Hospital | Federal Way | Washington |
United States | Hurley Medical Center | Flint | Michigan |
United States | Holy Cross Hospital | Fort Lauderdale | Florida |
United States | Florida Gynecologic Oncology | Fort Myers | Florida |
United States | Brooke Army Medical Center | Fort Sam Houston | Texas |
United States | Northeast Georgia Medical Center | Gainesville | Georgia |
United States | University of Texas Medical Branch | Galveston | Texas |
United States | Gynecologic Oncology of West Michigan PLLC | Grand Rapids | Michigan |
United States | East Carolina University | Greenville | North Carolina |
United States | Greenville Health System Cancer Institute-Faris | Greenville | South Carolina |
United States | Gynecologic Oncology Network | Greenville | North Carolina |
United States | Pitt County Memorial Hosp Inc. | Greenville | North Carolina |
United States | Hackensack University Medical CCOP | Hackensack | New Jersey |
United States | Hackensack University Medical Center | Hackensack | New Jersey |
United States | Virginia Oncology Associates-Hampton | Hampton | Virginia |
United States | Hartford Hospital | Hartford | Connecticut |
United States | The Methodist Hospital System | Houston | Texas |
United States | Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana |
United States | Saint Vincent Hospital and Health Care Center | Indianapolis | Indiana |
United States | University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa |
United States | Saint Dominic-Jackson Memorial Hospital | Jackson | Mississippi |
United States | University of Mississippi Medical Center | Jackson | Mississippi |
United States | East Tennessee State University | Johnson City | Tennessee |
United States | Jupiter Medical Center | Jupiter | Florida |
United States | Keesler Medical Center | Kessler AFB | Mississippi |
United States | Southeast Gynecologic Oncology Associates | Knoxville | Tennessee |
United States | Wilford Hall Medical Center | Lackland AFB | Texas |
United States | Marshfield Clinic - Ladysmith Center | Ladysmith | Wisconsin |
United States | Saint Clare Hospital | Lakewood | Washington |
United States | Sunrise Hospital and Medical Center | Las Vegas | Nevada |
United States | Women's Cancer Center of Nevada | Las Vegas | Nevada |
United States | Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire |
United States | University of Kentucky/Markey Cancer Center | Lexington | Kentucky |
United States | University of Arkansas for Medical Sciences | Little Rock | Arkansas |
United States | Long Beach Memorial Medical Center-Todd Cancer Institute | Long Beach | California |
United States | UCLA / Jonsson Comprehensive Cancer Center | Los Angeles | California |
United States | Norton Hospital Pavilion and Medical Campus | Louisville | Kentucky |
United States | Covenant Medical Center-Lakeside | Lubbock | Texas |
United States | Texas Tech University Health Sciences Center | Lubbock | Texas |
United States | University of Wisconsin Hospital and Clinics | Madison | Wisconsin |
United States | Marshfield Clinic | Marshfield | Wisconsin |
United States | Saint Joseph's Hospital | Marshfield | Wisconsin |
United States | University of Tennessee Health Science Center | Memphis | Tennessee |
United States | Lake University Ireland Cancer Center | Mentor | Ohio |
United States | University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida |
United States | Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin |
United States | Aurora Sinai Medical Center | Milwaukee | Wisconsin |
United States | Froedtert and the Medical College of Wisconsin | Milwaukee | Wisconsin |
United States | Winthrop University Hospital | Mineola | New York |
United States | University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota |
United States | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin |
United States | Meharry Medical College | Nashville | Tennessee |
United States | Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee |
United States | The Hospital of Central Connecticut | New Britain | Connecticut |
United States | Yale University | New Haven | Connecticut |
United States | Tulane University Health Sciences Center | New Orleans | Louisiana |
United States | Columbia University/Herbert Irving Cancer Center | New York | New York |
United States | Mount Sinai Medical Center | New York | New York |
United States | Rutgers New Jersey Medical School | Newark | New Jersey |
United States | Advocate Christ Medical Center | Oak Lawn | Illinois |
United States | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma |
United States | Capital Medical Center | Olympia | Washington |
United States | Providence - Saint Peter Hospital | Olympia | Washington |
United States | Nebraska Methodist Hospital | Omaha | Nebraska |
United States | UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California |
United States | Stanford Cancer Institute | Palo Alto | California |
United States | Fox Chase Cancer Center | Philadelphia | Pennsylvania |
United States | Temple University Hospital | Philadelphia | Pennsylvania |
United States | FirstHealth of the Carolinas-Moore Regional Hosiptal | Pinehurst | North Carolina |
United States | UPMC-Magee Womens Hospital | Pittsburgh | Pennsylvania |
United States | West Penn Hospital | Pittsburgh | Pennsylvania |
United States | Compass Oncology Rose Quarter | Portland | Oregon |
United States | Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon |
United States | Maine Medical Center-Bramhall Campus | Portland | Maine |
United States | Women and Infants Hospital | Providence | Rhode Island |
United States | MultiCare Good Samaritan Hospital | Puyallup | Washington |
United States | Black Hills Obstetrics and Gynecology | Rapid City | South Dakota |
United States | Marshfield Clinic at James Beck Cancer Center | Rhinelander | Wisconsin |
United States | Marshfield Clinic-Rice Lake Center | Rice Lake | Wisconsin |
United States | Carilion Clinic Gynecological Oncology | Roanoke | Virginia |
United States | University of California Davis Comprehensive Cancer Center | Sacramento | California |
United States | Saint Louis University Hospital | Saint Louis | Missouri |
United States | Washington University School of Medicine | Saint Louis | Missouri |
United States | UCSF Medical Center-Mount Zion | San Francisco | California |
United States | Memorial University Medical Center | Savannah | Georgia |
United States | Fred Hutchinson Cancer Research Center | Seattle | Washington |
United States | Pacific Gynecology Specialists | Seattle | Washington |
United States | Seattle Cancer Care Alliance | Seattle | Washington |
United States | Swedish Medical Center-First Hill | Seattle | Washington |
United States | University of Washington Medical Center | Seattle | Washington |
United States | Virginia Mason CCOP | Seattle | Washington |
United States | Virginia Mason Medical Center | Seattle | Washington |
United States | CHRISTUS Highland Medical Center | Shreveport | Louisiana |
United States | Avera Cancer Institute | Sioux Falls | South Dakota |
United States | Sanford Cancer Center-Oncology Clinic | Sioux Falls | South Dakota |
United States | Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota |
United States | Northern Indiana Cancer Research Consortium | South Bend | Indiana |
United States | Greenville Health System Cancer Institute-Spartanburg | Spartanburg | South Carolina |
United States | Baystate Medical Center | Springfield | Massachusetts |
United States | Cancer Research for the Ozarks NCORP | Springfield | Missouri |
United States | CoxHealth South Hospital | Springfield | Missouri |
United States | Memorial Medical Center | Springfield | Illinois |
United States | Mercy Hospital Springfield | Springfield | Missouri |
United States | Geisinger Medical Group | State College | Pennsylvania |
United States | Marshfield Clinic Cancer Care at Saint Michael's Hospital | Stevens Point | Wisconsin |
United States | Saint Michael's Hospital | Stevens Point | Wisconsin |
United States | Stony Brook University Medical Center | Stony Brook | New York |
United States | Olive View-University of California Los Angeles Medical Center | Sylmar | California |
United States | MultiCare Allenmore Hospital | Tacoma | Washington |
United States | Multicare Health System | Tacoma | Washington |
United States | MultiCare Tacoma General Hospital | Tacoma | Washington |
United States | Northwest Medical Specialties PLLC | Tacoma | Washington |
United States | Northwest NCI Community Oncology Research Program | Tacoma | Washington |
United States | Saint Joseph Medical Center | Tacoma | Washington |
United States | Scott and White Memorial Hospital | Temple | Texas |
United States | Cancer Care Associates-Midtown | Tulsa | Oklahoma |
United States | Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa | Oklahoma |
United States | MedStar Washington Hospital Center | Washington | District of Columbia |
United States | Sibley Memorial Hospital | Washington | District of Columbia |
United States | Marshfield Clinic-Wausau Center | Wausau | Wisconsin |
United States | Aurora West Allis Medical Center | West Allis | Wisconsin |
United States | Mercy Medical Center-West Lakes | West Des Moines | Iowa |
United States | Methodist West Hospital | West Des Moines | Iowa |
United States | Diagnostic and Treatment Center | Weston | Wisconsin |
United States | Marshfield Clinic - Weston Center | Weston | Wisconsin |
United States | Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania |
United States | Wake Forest University Health Sciences | Winston-Salem | North Carolina |
United States | Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin |
United States | University of Massachusetts Medical School | Worcester | Massachusetts |
United States | University of Massachusetts Memorial Health Care | Worcester | Massachusetts |
Lead Sponsor | Collaborator |
---|---|
Gynecologic Oncology Group | National Cancer Institute (NCI) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Collection of gynecological tumor specimens and serum from patients at GOG institutions | Baseline | No | |
Primary | Create a repository for long-term storage of these specimens | Baseline | No | |
Primary | Make available tissue and blood for proposed projects | Baseline | No |
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