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Evaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic Melanoma

Melanoma Clinical Trial

Official title:
A Phase II, Randomized, Open-Label Study Evaluating The Antitumor Activity Of MEDI-522, A Humanized Monoclonal Antibody Directed Against The Human Alpha V Beta 3 Integrin, ± Dacarbazine In Patients With Metastatic Melanoma

Clinical Trial Summary

The primary objectives of this study are:

- To explore the antitumor activity of MEDI-522 ± DTIC in patients with metastatic melanoma.

- To determine the safety of MEDI-522 ± DTIC in this patient population.

Clinical Trial Description

This is a Phase II, randomized, open-label, two-arm, multicenter study of MEDI 522 ± DTIC in previously untreated (other than adjuvant immunotherapy) patients with Stage IV metastatic melanoma (AJCC staging). ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00066196
Study type Interventional
Source MedImmune LLC
Contact
Status Completed
Phase Phase 2
Start date August 2003
Completion date June 2007
View Details
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