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Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults With Recurrent Medulloblastoma

Medulloblastoma Clinical Trial

Official title:
Infusion of Panobinostat (MTX110) Into the Fourth Ventricle or Tumor Resection Cavity in Children and Adults With Recurrent Medulloblastoma: A Pilot Study

Clinical Trial Summary

The purpose of this study is to establish the safety of infusions of panobinostat (MTX110) into the fourth ventricle of the brain or tumor resection cavity in patients with recurrent medulloblastoma and to assess the antitumor activity of simultaneous infusions of panobinostat (MTX110) into the fourth ventricle of the brain or resection cavity in patients with recurrent medulloblastoma based upon MRI scans and lumbar cerebrospinal fluid (CSF) cytology.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04315064
Study type Interventional
Source The University of Texas Health Science Center, Houston
Contact David IIan Sandberg, MD
Phone (713) 500-7370
Email David.I.Sandberg@uth.tmc.edu
Status Recruiting
Phase Early Phase 1
Start date April 21, 2020
Completion date December 30, 2025
View Details
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