Medication Therapy Management With Pharmacogenetic Testing

Status Completed

Clinical Trial Summary

This study aims to investigate the benefit and feasibility of providing pharmacogenetic (PGx) testing as part of a standard medication therapy management (MTM) session for patients taking multiple medications, a high-risk population for adverse drug reactions and non-response. Research participants will attend two MTM sessions and undergo PGx testing to inform the MTM plan. Participants will also complete 2 surveys pre and post-MTM/PGx testing. Data analysis will assess the impact of MTM/PGx testing on recommendations for drug dosing, clinical outcomes, patient satisfaction, and feasibility of service delivery. Safety issues are minimal with the primary risks being associated with loss of confidentiality, typical discomfort associated with acquiring blood samples, and genetic discrimination.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01970774
Study type	Interventional
Source	Duke University
Contact
Status	Completed
Phase	N/A
Start date	November 2013
Completion date	October 2014

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02816086` - A New Interdisciplinary Collaboration Structure to Improve Medication Safety in the Elderly	N/A
Withdrawn	`NCT04893395` - Assessment of the Impact of Clinical Pharmacogenomics on Real and Potential Medication Use in Veterans	N/A
Completed	`NCT02562352` - Team Approach to Polypharmacy Evaluation and Reduction	N/A
Completed	`NCT02863341` - Nursing Home Team-Care Deprescribing Study	N/A
Completed	`NCT04151797` - Impact of a Mobile Geriatric Team With a Pharmacist on the Optimisation of Prescriptions in Elderly Inpatients	N/A
Enrolling by invitation	`NCT06383364` - The Effect of a Medication Coordinator on the Quality of Patients Medication Treatment	N/A
Completed	`NCT03154489` - Effectiveness of a Multidisciplinary Medication Review With Follow-up for Patients Treated With Coumarin Anticoagulants in Primary Care	N/A
Completed	`NCT03257605` - A Pharmacist Implemented Pharmacogenomics Service in the Program of All-inclusive Care for the Elderly	N/A
Not yet recruiting	`NCT06310512` - Efficacy of Pharmacist Interventions Through the "Medication Therapy Management Pathway in Hypertensive Patients"	N/A
Recruiting	`NCT02942927` - Team Approach to Polypharmacy Evaluation and Reduction	N/A
Completed	`NCT03909035` - A Collaborative Approach to Medication Reviews for Older Patients With Polypharmacy	N/A
Recruiting	`NCT03557944` - Team Approach to Polypharmacy Evaluation and Reduction (Pharmacy)	N/A
Completed	`NCT02820129` - Effectiveness of a Medication Wallet Card	Phase 1
Terminated	`NCT03202264` - Team Approach to Polypharmacy Reduction to Improve Mobility Long-Term Care
Completed	`NCT03321058` - Polymedication-Check With Insight in Patients' Medication Organisation and Comprehension of Generics	N/A
Completed	`NCT02658604` - Home Medication Reviews by Pharmacists in Ontario, Canada	N/A
Withdrawn	`NCT05711771` - Medication Therapy Management (MTM) for a Medicaid Managed Care Population Within Patient-Centered Medical Homes
Recruiting	`NCT05553015` - A Real-World Registry Investigating TReprostInil sodiUM in Pulmonary Hypertension (Re-TRIUMPH)
Active, not recruiting	`NCT05278650` - Senior PharmAssist: Co-Design and Evaluation of a Toolkit to Promote Scalable Implementation	N/A
Recruiting	`NCT05351281` - Appropriate Medication Use in Dutch Terminal Care	N/A