Tools to Assess Medication Adherence

Medication Adherence Clinical Trial

Official title:

Evaluation of Tools to Assess Medication Adherence

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04772066
• Other study ID #: RECHMPL20_0662
• Status: Recruiting
• Start date: November 1, 2019
• Est. completion date: December 30, 2021

Study information

• Verified date: February 2021
• Source: University Hospital, Montpellier
• Contact: Cyril BREUKER, PharmD,Phd
• Phone: 467337121
• Email: c-breuker[@]chu-montpellier.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The issue of medication adherence (MA) has long been undestimated but is now growing interest due to both the increase of patients with chronic diseases and the aging of the population. According to the World Health Organization, only 50% of patients with chronic illnesses correctly follow physician's prescriptions in developed countries. Beyond the individual consequences that failure to adherence can engender (increased morbidity, mortality and hospitalizations), this concept also encompasses a collective dimension (risk of transmission of infectious diseases and increased health care costs). Today, improving MA would have more impact on human health than developping new medical therapies. That's why detecting non-adherence constitutes a major public health issue in which pharmacists play a significant role through medication reconciliation and patients' education.

The methods wildly used are based on indirect measurement: questionnaires completed by the patient himself or the Medication Possession Ratio (MPR). Each method has its own advantages and disadvantages, but none is considered as the gold standard. The Montpellier University Hospital set up a MA self-report scale ranging from 0 (low) to 10 (high adherence) in the various care units where the clinical pharmacy activity is deployed.

The purpose of this study was to assess the MA according to this numerical scale and the MPR calculation, and evaluate the correlation between these two methods.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 600
• Est. completion date: December 30, 2021
• Est. primary completion date: December 1, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 100 Years

Eligibility

Inclusion criteria:

• Subjects aged over 18 years old, admitted in a care unit of Montpellier University Hospital where the clinical pharmacy activity is deployed

Exclusion criteria:

• Subjects without any medication therapy at home

Related Conditions & MeSH terms

• Medication Adherence

Intervention

Other:
• Measure of medication adherence
Measure of medication adherence

Locations

Country	Name	City	State
France	Uhmontpellier	Montpellier

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Montpellier

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Self-reported MA according to self-reported medication adherence scale	Self-reported MA according to self-reported MA scale : The self-report scale ranges from 0 (low) to 10 (high adherence)	1 day
Primary	MA according to Medication Possession Ratio (MPR) calculation	MA according to Medication Possession Ratio (MPR) calculation	1 day
Secondary	Number of patients with medication non-adherence according to self-reported MA scale and MPR calculation	Number of patients with medication non-adherence according to self-reported MA scale and MPR calculation	1 day
Secondary	Variables associated with medication non-adherence	Variables associated with medication non-adherence	1 day