Polymedication-Check With Insight in Patients' Medication Organisation and Comprehension of Generics

Medication Adherence Clinical Trial

Official title:

Polymedikations-Check Und Medikamenten-Organisation im Alltag

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03321058
• Other study ID #: PMC-Medication-Organisation
• Status: Completed
• Phase: N/A
• First received: June 1, 2017
• Last updated: October 24, 2017
• Start date: January 6, 2017
• Est. completion date: October 24, 2017

Study information

• Verified date: October 2017
• Source: University Hospital, Basel, Switzerland
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Patients using multiple drugs including generics have found different solutions to manage their medication. During a Polymedication-Check (medication review type 2a service in community pharmacies) additional information about the organisation of patients' medication in daily life will be compiled in Swiss community pharmacies. Data will allow to better address patients' needs in their medication organisation and comprehension of generics.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 125
• Est. completion date: October 24, 2017
• Est. primary completion date: October 1, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• at least 4 medicines for at least 3 months

• at least 1 generic drug

• at least 1 medicine of ATC code cardiovascular system (C01-10)

Exclusion Criteria:

• medication provided in Multicompartment Compliance Aid or similar device by specific service (pharmacy, elderly home, home care)

Related Conditions & MeSH terms

• Medication Adherence
• Medication Therapy Management

Intervention

Behavioral:
• Assessment
Assessment of patients' medication organisation and comprehension of generics

Locations

Country	Name	City	State
Switzerland	University of Basel	Basel	Basel-Stadt

Sponsors (2)

Lead Sponsor	Collaborator
University Hospital, Basel, Switzerland	University of Basel

Country where clinical trial is conducted

Switzerland, 

References & Publications (4)

Håkonsen H, Eilertsen M, Borge H, Toverud EL. Generic substitution: additional challenge for adherence in hypertensive patients? Curr Med Res Opin. 2009 Oct;25(10):2515-21. doi: 10.1185/03007990903192223. — View Citation

Messerli M, Blozik E, Vriends N, Hersberger KE. Impact of a community pharmacist-led medication review on medicines use in patients on polypharmacy--a prospective randomised controlled trial. BMC Health Serv Res. 2016 Apr 23;16:145. doi: 10.1186/s12913-016-1384-8. — View Citation

Nunney J, Raynor DK, Knapp P, Closs SJ. How do the attitudes and beliefs of older people and healthcare professionals impact on the use of multi-compartment compliance aids?: a qualitative study using grounded theory. Drugs Aging. 2011 May 1;28(5):403-14. doi: 10.2165/11587180-000000000-00000. Review. — View Citation

Olsson E, Kälvemark Sporrong S. Pharmacists' experiences and attitudes regarding generic drugs and generic substitution: two sides of the coin. Int J Pharm Pract. 2012 Dec;20(6):377-83. doi: 10.1111/j.2042-7174.2012.00214.x. Epub 2012 Jun 1. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Insight in patients' organisation of polymedication	Patients organise their multiple medications differently in daily life. The study will investigate the different organisation strategies to get a better understanding of patients' behaviour. The behaviour is assessed with a questionnaire containing 14 questions on the management of medication including single choice, multiple choice and free text questions. As example the number of patients already using a medication organisation system will be assessed, the number of patients using a weekly or daily pillbox will be assessed, and who is filling the medication organisation system.	retrospective 3 months
Primary	Insight in patients' comprehension of generics	Patients have a different comprehension of generics including their advantages and disadvantages. The study will investigate patients' comprehension of generics to get a better understanding of patients' behaviour. The comprehension is assessed with a questionnaire containing 4 questions on the believes about generics including single choice, multiple choice and free text questions. As example the number of patients knowing that they use generics is assessed and the patient's personal opinion on advantages and disadvantages of generics is investigated.	retrospective 3 months
Secondary	Number of patients using Multicompartment Compliance Aids.	Assessment of proportion of patients already using Multicompartment Compliance Aids prior to interview.	retrospective 3 months
Secondary	Number of substitutable medicines.	Assessment of number of brand name medication which could be substituted by generic medication and willingness of pharmacists to recommend generic medicines.	retrospective 3 months
Secondary	Swallowing difficulties	Prevalence of present and/or past swallowing difficulties and coping strategies will be assessed. A specific question (from SWAMECO) on the experienced swallowing difficulties is asked and will be answered on a visual analog scale (0 to 100%). If swallowing-difficulties are present, 2 more questions are asked: Which medication is difficult to swallow and how medication is altered in order to be able to swallow them.	retrospective 3 months
Secondary	Recommended use of Multicompartment Compliance Aids	Number of recommended use of Multicompartment Compliance Aids by pharmacists.	retrospective 3 months