Improvement of Intentional and Unintentional Non-adherence in the Elderly

Medication Adherence Clinical Trial

Official title:

Improvement of Intentional and Unintentional Non-adherence in the Elderly. Importance of Pharmaceutical Care, Generic Substitution, Non-prescription Drugs, Herbal Medicine and Dietary Supplements

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01512238
• Other study ID #: CO01
• Status: Completed
• Phase: N/A
• First received: January 4, 2012
• Last updated: September 30, 2014
• Start date: February 2010
• Est. completion date: November 2013

Study information

• Verified date: December 2013
• Source: University of Aarhus
• Contact: n/a
• Is FDA regulated: No
• Health authority: Denmark: Danish Dataprotection Agency
• Study type: Observational

Clinical Trial Summary

The purpose is to study if different factors influence medicine adherence in elderly people. In this study number of generic substitution and use of non-prescription drugs, herbal medicine and dietary supplement is in focus.

Description:

The purpose of this study is to describe in the elderly:

1. Association between medicine adherence and number of generic substitution

2. Association between medicine adherence and use of non-prescription drugs, herbal medicine and dietary supplements and interaction between 'prescription drugs' and 'non-prescription drugs, herbal medicine and dietary supplements'

3. Intentional and unintentional non-adherence

Some of the data in the present study were originally collected as part of a major research project 'Methods for Improving Compliance with Medicine Intake' (MICMI). The study sample of 945 persons was randomly selected into three groups: two intervention groups and one control group. Interventions were pharmaceutical care and an electronic reminder system. All groups were followed for one year.

Data in the present study is from the pharmaceutical care group and the control group, and is descriptive.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 630
• Est. completion date: November 2013
• Est. primary completion date: January 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Aged 65 years or older

• Living in their own homes

• Without assistance to medicine administration

• Living in the Municipality of Aarhus, Denmark

• Long-term treatment with > 4 prescription drugs

Exclusion Criteria:

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

• Medication Adherence

Intervention

Other:
• Pharmaceutical care
Information about medicine, sideeffect, adherence

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Aarhus

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Medicine adherence		One year	No
Secondary	Number of generic substitution		One year	No
Secondary	Use of non-prescription drugs, herbal medicine and dietary supplements and frequency of interaction between 'prescription drugs' and 'non-prescription drugs, herbal medicine and dietary supplements'		Actually day	No
Secondary	Intentional and unintentional non-adherence association with generic substitution and use of non-prescription drugs, herbal medicine and dietary supplements		One year	No