Mechanical Ventilation Clinical Trial
Official title:
In a Developing Country; What is the Fate of Hematologic Cancer Patients Requiring Mechanical Ventilation for More Than One Day? A Prospective Cohort Study
This observational cohort aimed to re-evaluate the outcome of hematologic cancer patients admitted to the intensive care unit of Mansoura oncology center through a cohort study as regards their need for mechanical ventilation during two years.
It has been believed for many years that the scene of cancer patients requiring mechanical ventilation is frustrating. The needed life support measures drain much of health resources and add a significant burden on the patient's family. Many factors have been responsible for the high mortality rates among hematologic cancer patients admitted to intensive care unit. Among of these factors, the invasive treatments that are frequently employed in today's intensive care unit. These procedures give chance for development of severe infection and multiple organ failure which are common events in immune-compromised patients (e.g. neutropenia) and in those exposed to chemotherapy. The most common form of organ failure in those patients is acute respiratory failure which is a major predictor of mortality in that population. The prognosis of such failure may vary depending on its causes and severity, co morbidity, associated acute organ failure and characters of the underlying malignancy. After the recent advances in the field of intensive care and shedding light on the benefits of the noninvasive ventilation in immune-compromised patients, the overall survival rate of cancer patients admitted to intensive care unit are improving. ;
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05921656 -
Construction and Evaluation of Airway Leakage Risk Model of Patients With Endotracheal Tube
|
||
| Recruiting |
NCT03941002 -
Continuous Evaluation of Diaphragm Function
|
N/A | |
| Withdrawn |
NCT04288076 -
The Brain and Lung Interaction (BALI) Study
|
N/A | |
| Completed |
NCT03031860 -
Semi-quantitative Cough Strength Score (SCSS)
|
N/A | |
| Completed |
NCT02312869 -
Local Assessment of Management of Burn Patients
|
N/A | |
| Completed |
NCT02545621 -
A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study
|
||
| Completed |
NCT01885442 -
TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients
|
N/A | |
| Completed |
NCT01204281 -
Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients
|
Phase 4 | |
| Terminated |
NCT01059929 -
Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)
|
Phase 4 | |
| Completed |
NCT00824239 -
Intermittent Sedation Versus Daily Interruption of Sedation in Mechanically Ventilated Patients
|
Phase 3 | |
| Completed |
NCT00529347 -
Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects of Changes in Ventilator Parameters on Breathing Pattern
|
Phase 1 | |
| Unknown status |
NCT00260676 -
Protective Ventilatory Strategy in Potential Organ Donors
|
Phase 3 | |
| Terminated |
NCT00205517 -
Sedation and Psychopharmacology in Critical Care
|
N/A | |
| Completed |
NCT03281785 -
Ultrasound of Diaphragmatic Musculature in Mechanically Ventilated Patients.
|
N/A | |
| Recruiting |
NCT04110613 -
RCT: Early Feeding After PEG Placement
|
N/A | |
| Completed |
NCT04410783 -
The Emergency Department Sedation Pilot Trial
|
N/A | |
| Recruiting |
NCT04821453 -
NAVA vs. CMV Crossover in Severe BPD
|
N/A | |
| Completed |
NCT03930147 -
Ventilation With ASV Mode in Children
|
N/A | |
| Recruiting |
NCT05029167 -
REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)
|
N/A | |
| Recruiting |
NCT04849039 -
Lung Microbiota and VAP Development (PULMIVAP)
|