Marijuana Dependence Clinical Trial
— MTP4Official title:
Individualized Assessment and Treatment for Marijuana Dependence: Treatment Mechanisms
Verified date | June 2019 |
Source | UConn Health |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Marijuana is the most commonly used illicit drug in the US, but treatment for marijuana dependence is not fully effective. In the current proposal we are exploring the idea that more tailored teaching of coping skills may result in improved outcomes for marijuana-dependence than those seen thus far. Participants will be 275 men and women meeting criteria for marijuana dependence and randomly assigned to 9 sessions of treatment in one of 4 treatment conditions: Standardized MET plus CB (SMET-CB); SMET+ CM (SMET-CB-CM); IATP; or IATP + CM (IATP-CM). Patients in all treatments will engage in ES via cell-phone for two weeks prior to treatment, for a weekly period during treatment, for another week after treatment has ended, and for two weekly periods at months 8 and 14. In the IATP conditions, the information gathered from the pretreatment and during-treatment ES periods will provide data for a functional analysis of patients' drug use and urges to use. It is hypothesized that IATP conditions will yield significantly better coping skills acquisition than SMET-CB conditions, both at posttreatment and at extended follow-ups, and that change in coping skills will predict better outcomes for the IATP conditions
Status | Completed |
Enrollment | 198 |
Est. completion date | April 2018 |
Est. primary completion date | April 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 99 Years |
Eligibility |
Inclusion Criteria: - at least 18 yrs old - meet Diagnostic and Statistical Manual IV (DSM-IV) criteria for Cannabis Dependence - be willing to accept random assignment to any of the 4 treatment conditions Exclusion Criteria: - acute medical/psychiatric problems that require inpatient treatment (e.g., acute psychosis, severe depression, suicide/homicide risk) - reading ability below the fifth grade level - lack of reliable transportation - excessive commuting distance. |
Country | Name | City | State |
---|---|---|---|
United States | University of Connecticut Health Center | Farmington | Connecticut |
Lead Sponsor | Collaborator |
---|---|
UConn Health | National Institute on Drug Abuse (NIDA) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Marijuana Use | Marijuana use measured in terms of Days of use in every 90-day period | every 3 months | |
Secondary | Coping Skills | Coping Skills measured using the Coping Skills Survey, administered every 3 months | every 3 months |
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