Topical Endoxifen in Women — CREME

Mammographic Breast Density Clinical Trial

Official title:
Karma CREME-1: A Double-blind, Placebo-controlled, Three-armed, Pilot Study of the Effects, Safety and Tolerability of Topical Endoxifen in Women Within the Karma Cohort

Status Completed

Clinical Trial Summary

Karma CREME-1 consisted of 90 participants from the Karma Cohort. The major focus of the pilot trial was to estimate time to mammographic density change. The primary objective was to determine the effect size of the breast density change between topical placebo and two doses of topical endoxifen.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Mammographic Breast Density

Clinical Trial Details

NCT number	NCT04616430
Study type	Interventional
Source	Atossa Genetics, Inc.
Contact
Status	Completed
Phase	Phase 2
Start date	April 9, 2018
Completion date	September 4, 2019

View Details

See also
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Completed	`NCT00470561` - Effect of Aspirin on Mammogram Density in Healthy Postmenopausal Women With a Moderate or High Level of Breast Density	N/A
Recruiting	`NCT04498013` - Study of the Effects of Cyclodynon on Reducing the Cumulative Risk of Breast Cancer Development in a Female Aged 40-52	Phase 4
Terminated	`NCT03199963` - Trial of 4-Hydroxytamoxifen (4-OHT) Gel in Women Aimed at Reducing Dense Breast Tissue	Phase 3