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Malocclusion clinical trials

View clinical trials related to Malocclusion.

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NCT ID: NCT00957489 Terminated - Clinical trials for Class II Division 1 Malocclusion

A Prospective Randomized Controlled Trial to Evaluate the Effectiveness of the Two Different Appliances in the Treatment of Class II Division 1 Malocclusion

Start date: January 2007
Phase: N/A
Study type: Interventional

Twin-Block treatment and Dynamax treatment for Class II division 1 malocclusion do not have different effects with regards to treatment duration, the quality of dento-occlusal outcome, skeletal and soft tissue profile, patient discomfort and gingival health.

NCT ID: NCT00830947 Completed - Malocclusion Clinical Trials

Effect of Cyclic Loading (Vibration) on Orthodontic Tooth Movement

Start date: February 2009
Phase: Phase 3
Study type: Interventional

To gather data indicating whether or not the OrthoAccel device speeds tooth movement in people who use orthodontics (braces).

NCT ID: NCT00688233 Recruiting - Clinical trials for Malocclusion, Angle Class II

Effect of the Innovated Seifi's Functional Appliance on Skeletal and Dentoalveolar Changes of Class II/ 1, Deep Bite

Seifi-Fx
Start date: December 2007
Phase: Phase 1
Study type: Interventional

For improving the appearance of protruded upper front teeth when lower front teeth may touch palatal mucosa or have proximity to that; the innovated Seifi's Functional Appliance may be used.

NCT ID: NCT00485602 Not yet recruiting - Malocclusion Clinical Trials

Orthodontic Treatment With a Part-Time Wearing Esthetic Removable Appliance

Start date: December 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The trial is aimed to investigate an orthodontic treatment with a new removable-part-time-wearing appliance, based on "High-Tech" technology. The appliance should be wear only 12-14 hours a day, and is made of a single silicone aligner, made specifically for the patient, using 3-D screening technology of the patient's malocclusion. The aligner has a designed pathway "built-in" for the tooth to move, from the original position of the malocclusion to the "end point" - the correct position. The force system, that is needed in order to generate tooth movement, is produced by tiny air-balloons which are incorporated in the aligner. The study hypothesis is, that an orthodontic treatment can be done successfully with this part-time wearing appliance.

NCT ID: NCT00248014 Completed - Clinical trials for CLASS II DIVISION 1 MALOCCLUSION

Response of Individuals With Class II Malocclusion

Start date: October 2005
Phase: Phase 2
Study type: Interventional

This investigation aims at distinguishing the subjects that react in a favorable way to the treatment protocol we propose for the Class II treatment

NCT ID: NCT00155311 Completed - Malocclusion Clinical Trials

The Regulation of Osteoprotegerin by Mechanical Stimulation

Start date: January 2005
Phase: Phase 1
Study type: Interventional

To test whether levels of OPG can be changed during orthodontic treatment. Alveolar bone samples will be collected from partially impacted third molars after orthodontic uprighting for different period of time in volunteers. In situ hybridization and immunohistochemistry analysis for OPG and RANKL will reveal their roles in this physiological process.

NCT ID: NCT00099814 Completed - Clinical trials for Malocclusion, Angle Class III

Periodontal Ligament Stress Level and Tooth Movement

Start date: March 2004
Phase: Phase 1
Study type: Interventional

Orthodontic treatment requires application of force systems to individual teeth or groups of teeth, which results in a cellular response with periodontal ligament (PDL) and alveolar bone remodeling. The forces applied must be of sufficient magnitude and duration to exceed the normal physiologic threshold associated with daily oral function. Excessive force levels will result in areas of tissue necrosis with delayed tooth movement and increased risk of root resorption. Although orthodontic tooth movement is achieved in a large segment of the population, the optimum force level has not been defined. The optimum force for tooth movement depends on individual root geometry as well as biologic characteristics of surrounding tissue including bone density, periodontal thickness, and fluid dynamics. Because experimental and clinical techniques are generally limited to known complex force systems, biomechanical modeling has become a necessity. Such models must be validated with well-controlled clinical studies that evaluate orthodontic tooth movement over an extended distance. The ultimate goal would be development of a computer simulation model to predict tooth movement in the clinical setting. The primary objective of this study is to test controlled clinical data with a biomechanical model of the tooth and supporting tissues for distal movement of the human maxillary canine tooth (of known root geometry) in response to various 3D force systems that produce different levels of stress in the supporting tissues. Secondary objectives include evaluation of rate of bodily tooth canine movement with two known compressive stress levels (13 and 22 kPa), evaluation of three different reference systems to measure rate of tooth movement, and evaluation of an implant placed in the roof of the mouth (palatal implant) for orthodontic anchorage in adolescent patients. The rate of translation (bodily) tooth movement of the maxillary canine tooth will be significantly greater with 22kPa compared to 13kPa compressive stress applied to the periodontal ligament, and this difference can be predicted by appropriate mathematical/numerical models of the tooth and supporting tissues.

NCT ID: NCT00067379 Active, not recruiting - Malocclusion Clinical Trials

Early Orthodontic Intervention Under Medicaid

Start date: April 2003
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to examine the usefulness of early orthodontic intervention as a means of increasing access to orthodontic services for children of low-income families.