Malignant Pleural Mesothelioma Clinical Trial
Official title:
NGR010: A Phase II Study of NGR-hTNF Administered as Single Agent Every 3 Weeks or Weekly in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma Previously Treated With no More Than One Systemic Therapeutic Regimen
The main objective of the trial is to document the progression free survival (PFS) in
advanced or metastatic malignant pleural mesothelioma patients treated with NGR-hTNF as
single agent.
Safety will be established by clinical and laboratory assessment according to NCI-CTC
criteria.
This is a phase II, open-label, non-randomized study that will be conducted in patients affected by advanced or metastatic malignant pleural mesothelioma previously treated with no more than one systemic therapeutic regimen , that will be conducted using Simon's two-stage design method. ;
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