Norris ORIEN Total Cancer Care

Status Recruiting

Clinical Trial Summary

This research trial collects biological samples and clinical information to create a repository of data from patients with cancer or a predisposition for cancer. Combining genetic information from biological samples and clinical data may lead to more knowledge about why certain cancers respond to treatment and help create more personalized medicine.

Clinical Trial Description

PRIMARY OBJECTIVES: I. To establish a longitudinal study of clinical and related data from patients with or at risk for cancer. II. To establish a large biospecimen repository that is linked to clinical and related data. III. To follow patients through their lifetime though passive or active follow-up. IV. To use clinical data, tissues, other biological samples and derived molecular data in the Total Cancer Care Protocol (TCCP) repositories to match patients in this TCCP study to future studies. OUTLINE: Patients undergo collection of blood during a regular care visit or not up to 4 times a year. Extra tissue is collected after removal during standard of care surgery and patients may undergo additional tumor sampling (needle passes) at the time of planned diagnostic biopsies. During bone marrow biopsy, the doctor may reposition the needle up to 3 times, and bone marrow for research will not be collected more than 4 times per year. Patients may undergo additional collection of other biological samples such as saliva, sputum, urine, feces, hair, and surface skin swabs for analysis. Patients also receive surveys or questionnaires to collect demographics, medical, family, and nutritional history, cancer predisposing risk factors, quality of life data, and quality of care data. After completion of study, patients are followed up periodically. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02970045
Study type	Observational
Source	University of Southern California
Contact	Melissa Woodhouse, MHA, MPH
Phone	323-865-0489
Email	Melissa.woodhouse@med.usc.edu
Status	Recruiting
Phase
Start date	May 2, 2016
Completion date	May 2, 2037

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05094804` - A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents	Phase 1/Phase 2
Active, not recruiting	`NCT02243592` - Molecular Profiling in Tissue Samples From Patients With Cancer Who Are Exceptional Responders to Treatment
Completed	`NCT03445572` - Meditative Slow Breathing or Isha Kriya Meditation in Improving Cancer-Related Symptoms in Hospitalized Participants With Cancer	N/A
Active, not recruiting	`NCT02860039` - High Dose Flu Vaccine in Treating Children Who Have Undergone Donor Stem Cell Transplant	Phase 2
Completed	`NCT01946217` - Factors Affecting Patient Participation in AIDS Malignancy Clinical Trials Consortium Clinical Trials	N/A
Completed	`NCT01635413` - Group Exercise Training for Functional Improvement After Treatment (The GET FIT Trial)	N/A
Completed	`NCT00026169` - Imatinib Mesylate in Treating Patients With Advanced Cancer and Kidney Failure	Phase 1
Recruiting	`NCT04534075` - Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial	Phase 3
Active, not recruiting	`NCT01806129` - Reproductive Health Program in Patients With Cancer	N/A
Recruiting	`NCT03915717` - Observational Study of Outcomes After EchoMark and EchoSure-based Free Flap Monitoring
Recruiting	`NCT02280161` - Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer
Recruiting	`NCT05520281` - Short-term Psychodynamic Psychotherapy in Serious Physical Illness	N/A
Terminated	`NCT00532064` - Cardiac Biomarkers in Early Detection of Cardiotoxicity in Patients Receiving Sunitinib or Sorafenib Chemotherapy
Completed	`NCT04990882` - FAPI PET/CT Prospective Interobserver Agreement
Completed	`NCT01896778` - Body Warming in Improving Blood Flow and Oxygen Delivery to Tumors in Patients With Cancer	N/A
Recruiting	`NCT05770102` - DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Teenage/Young Adults and Paediatric Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition	Phase 2/Phase 3
Recruiting	`NCT06090266` - A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents	Phase 1/Phase 2
Recruiting	`NCT05886764` - Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials	N/A
Completed	`NCT01432431` - Spiritual Care in Improving Quality of Life of Patients, Caregivers, and Hospital Staff	N/A
Completed	`NCT01506440` - Cognitive Assessments in Patients With Cancer Undergoing Chemotherapy