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Single Low Dose Tafenoquine to Reduce P. Falciparum Transmission in Mali (NECTAR2) — NECTAR2  

Malaria, Falciparum Clinical Trial

Official title:
Single Low Dose Tafenoquine to Reduce P. Falciparum Transmission in Mali (NECTAR2)

Clinical Trial Summary

The purpose of this study is to assess the gametocytocidal and transmission reducing activity of dihydroartemisinin-piperaquine (DP) with and without various low doses of tafenoquine (TQ; 1.66mg/kg, 0.83mg/kg, or 0.415mg/kg). Outcome measures will include infectivity to mosquitoes at 2 and 7 days after treatment, gametocyte density throughout follow-up, and safety measures including haemoglobin density.

Clinical Trial Description

Full protocol available on request. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04609098
Study type Interventional
Source London School of Hygiene and Tropical Medicine
Contact
Status Completed
Phase Phase 2
Start date October 29, 2020
Completion date December 23, 2020
View Details
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