Perception of Baby's Painful Cry in fMRI

Status Completed

Clinical Trial Summary

Crying is the primary signaling strategy available to the human newborn for eliciting parental care. Yet, the investigators only have superficial understanding of the information carried by cries, and how this information is perceived by parents. Using modern tools of sound processing and functional Magnetic Resonance Imaging (fMRI) experiment, this study aims to investigate cry-induced brain activation in adult depending on the cry's acoustic properties expressing various degrees of stress and distress levels. For that, Adults will be tested inside a fMRI magnet to determine their brain activations elicited by different babies cries according to whether the cry was evoked in a pain situation or not. The cerebral activity will be investigated in relation to acoustic features of cries (e.g. with pitch and/or roughness variations). To test if the gender or parentally of adult listeners influence their perceptions and brain responses, the task will be applied to 2 different groups (men and women not-parents). The hypothesis is that the brain of adult listeners will be able to discriminate adequately the intensity of the pain mediated by the cries. This process should involve brain areas such as the insular and the orbito frontal cortex that are known to participate in the integration of pain intensity and pain controls. The experiment should also determine which one of the acoustic features is able to transmit pain and to recruit brain areas involved in pain processes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03190486
Study type	Interventional
Source	Centre Hospitalier Universitaire de Saint Etienne
Contact
Status	Completed
Phase	N/A
Start date	July 24, 2017
Completion date	July 5, 2018

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT03785171` - Predicative Value of Multimodal MRI in Moyamoya Disease
Not yet recruiting	`NCT03726788` - Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis	Phase 2
Active, not recruiting	`NCT01956409` - Proton MR Spectroscopy and 18F-Fluorocholine PET for Breast Cancer Diagnosis	Phase 4
Completed	`NCT01660841` - Safety and Efficacy of Gadobutrol 1.0 Molar in Japanese Subjects for CNS Imaging	Phase 3
Recruiting	`NCT03635619` - The Application of 3T MRI in Esophageal Cancer
Recruiting	`NCT03658343` - T2* MRI Analysis for Sarcoma	N/A
Recruiting	`NCT04555642` - Early Diagnosis of Therapy-associated Cardiotoxicity Basing on Multi-tracer Multimodality PET/MRI
Active, not recruiting	`NCT03441867` - Neuroimaging Biomarker for Seizures	N/A
Recruiting	`NCT04850001` - Cognitive Decline in Asymptomatic Intracranial Stenosis Patients: A 1-Year Follow-Up Study
Not yet recruiting	`NCT05816213` - Point-of-care Low-field MRI in Acute Stroke
Active, not recruiting	`NCT05498623` - MR Fingerprinting for Diagnostic of Prostate Cancer
Recruiting	`NCT04996615` - Artificial Intelligence Analysis for Magnetic Resonance Imaging in Screening Breast Cancer in High-risk Women
Recruiting	`NCT04257747` - Qualitative and Quantitative Evaluation of Vascular Flows of Radial, Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI	N/A
Recruiting	`NCT05889117` - Brain Stimulation for Concussion	N/A
Completed	`NCT02540967` - Drug Use Investigation of Gadovist.
Completed	`NCT05103189` - 4D-flow Cardiac MRI to Assess Pulmonary Arterial Pressure in Pulmonary Hypertension	N/A
Completed	`NCT02567318` - Is the Volume of the Caudate Nuclei Associated With Area of Secondary Hyperalgesia?	N/A
Recruiting	`NCT02834585` - Magnetic Resonance Imaging or Ultrasound in Soft Tissue Tumors (MUSTT)	N/A
Active, not recruiting	`NCT02446665` - Disease Status in Primary Sclerosing Cholangitis by Elastography	N/A
Completed	`NCT01721785` - Diagnostic Value of Novel MR Imaging Techniques for the Primary Staging and Restaging of Rectal Cancer	N/A