Magnetic Resonance Imaging Clinical Trial
Official title:
Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
Whole body MRI will be performed in patients with neurofibromatosis Type 1
PURPOSE 1:
To determine the total tumor load (neurofibroma) and to diagnose plexiform neurofibromas or
malignant peripheral nerve sheath tumors. All patients will be scanned two years after the
baseline whole body MRI to investigate to investigate the changes of total tumor load.
PURPOSE 2: added value of diffusion weighted imaging in diagnosis of high-risk neurofibromas
PURPOSE 3 : to determine the apparent diffusion coefficient of the malignant nerve sheath
tumors and neurofibroma.
PURPOSE 4 : correlation between histopathology of the surgically resected
neurofibroma/malignant nerve sheath tumors and MRI findings
n/a
Observational Model: Case-Only, Time Perspective: Prospective
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