Bevacizumab in Combination With Visudyne Photodynamic Therapy (PDT)

Status Completed

Clinical Trial Summary

To evaluate safety, visual acuity outcomes, persistence of choroidal neovascular leakage, and the number of treatments of combination intravitreal bevacizumab and verteporfin photodynamic therapy at standard or reduced fluence level in patients with subfoveal CNV due to age-related macular degeneration.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00729846
Study type	Interventional
Source	California Retina Consultants
Contact
Status	Completed
Phase	Phase 2
Start date	May 2006
Completion date	July 2009

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04292912` - A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Participants With Diabetic Macular Edema	Phase 1
Recruiting	`NCT05976139` - Micropulsed Laser in Patients With Macular Oedema in Retinal Dystrophies	N/A
Completed	`NCT03660371` - ILM Peeling in PDR Patients Undergoing PPV for VH	N/A
Completed	`NCT03660345` - PPV With Internal Limiting Membrane Peeling for Treatment-Naïve DME	Phase 3
Completed	`NCT01660802` - Safety and Efficacy Study of Dexamethasone in the Treatment of Patients With Macular Edema Following Retinal Vein Occlusion (RVO)	Phase 3
Completed	`NCT01908816` - An Open-label Extended Clinical Protocol of Ranibizumab to Evaluate Safety and Efficacy in Rare VEGF Driven Ocular Diseases.	Phase 3
Completed	`NCT04592419` - A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO)	Phase 3
Completed	`NCT02867735` - A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular Edema	Phase 1
Completed	`NCT02623673` - Simultaneous Therapy With Intravitreal Dexamethasone Implant and Bevacizumab for the Treatment of Macular Edema	N/A
Terminated	`NCT01946399` - Ozurdex Implant for Macular Edema After Treatment Failure With Anti-VEGF	N/A
Completed	`NCT01428388` - Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein Occlusion	N/A
Completed	`NCT01231633` - Comparison of Initial Ozurdex (Dexamethasone Implant) to Avastin (Bevacizumab) for Treatment of Macular Edema Caused by Central Retinal Vein Occlusion (CRVO)	N/A
Recruiting	`NCT01023113` - To Compare Visual Field Impairment in Conventional Double Frequency Nd: YAG Panretinal Photocoagulation With PASCAL Panretinal Photocoagulation	N/A
Terminated	`NCT00918554` - Efficacy Study of Methotrexate to Treat Sarcoid-associated Uveitis	Phase 4
Terminated	`NCT00969293` - Study to Assess the Safety and Tolerability of a Single Administration of FOV2302 (Ecallantide) in Patients With Macular Edema Associated With Central Retinal Vein Occlusion	Phase 1
Completed	`NCT00970957` - Safety and Effectiveness of Bevacizumab Intravitreal Injections in the Treatment of Macular Edema Secondary to Retinal Vein Occlusion	Phase 3
Completed	`NCT00476593` - Retinal OCT and (mfERG) Related to Age, Sex, and the Use of Anti-inflammatory Medications	N/A
Completed	`NCT00411970` - 20- Versus 23- Gauge System for Pars Plana Vitrectomy	Phase 4
Completed	`NCT00668239` - Diffuse Diabetic Maculopathy With Intravitreal Triamcinolone or Laser	N/A
Terminated	`NCT01939691` - Macular Edema Nepafenac vs. Difluprednate Uveitis Trial	Phase 4