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Macular Edema clinical trials

View clinical trials related to Macular Edema.

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NCT ID: NCT01411696 Completed - Macular Edema Clinical Trials

Retrospective Study in Patients Receiving Two or More OZURDEX® Injections for Retinal Vein Occlusion (RVO)

Start date: July 2011
Phase: N/A
Study type: Observational

This is a retrospective data collection study to evaluate the efficacy, safety, and re-injection interval of OZURDEX® in the treatment of macular edema due to RVO. Following informed consent, there were no patient study visits. All data was collected via chart review.

NCT ID: NCT01411254 Completed - Clinical trials for Diabetic Macular Edema

Efficacy and Safety of Betamethasone Microsphere in Patients With Diabetic Macular Edema (TSUBASA)

Start date: n/a
Phase: Phase 2/Phase 3
Study type: Interventional

This study will evaluate the efficacy and safety of Betamethasone Microsphere (DE-102) for diabetic macular edema.

NCT ID: NCT01410201 Terminated - Macular Edema Clinical Trials

Dexamethasone Intravitreal Implant After Vitrectomy For Epiretinal Membrane

OZURDEX2
Start date: August 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of dexamethasone intravitreal implant (Ozurdex) in combination with pars plana vitrectomy and membrane peeling for idiopathic epiretinal membrane (ERM).

NCT ID: NCT01396083 Completed - Macular Edema Clinical Trials

Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With Central Retinal Vein Occlusion (CRVO)

COMRADE-C
Start date: August 2011
Phase: Phase 3
Study type: Interventional

This clinical trial is designed to compare ranibizumab in comparison with Dexamethasone implant® after 6 months of treatment. In the study arm Lucentis will be given monthly in a pro re nata scheme whereas the comparator Dexamethasone implant is given once at Month 0 with sham injections PRN afterwards.

NCT ID: NCT01396057 Completed - Macular Edema Clinical Trials

Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With Branch Retinal Vein Occlusion (BRVO)

COMRADE-B
Start date: July 2011
Phase: Phase 3
Study type: Interventional

This clinical trial is designed to compare ranibizumab in comparison with Dexamethasone implant after 6 months of treatment. In the study arm Ranibizumab will be given monthly in a pro re nata scheme whereas the comparator Dexamethasone implant is given once at Month 0 with sham injections PRN afterwards.

NCT ID: NCT01395069 Completed - Macular Edema Clinical Trials

Prophylactic Nepafenac and Ketorolac Versus Placebo in Patients Undergoing Cataract Surgery

PNK
Start date: February 2010
Phase: Phase 4
Study type: Interventional

Assess prophylactic efficacy of topical non-steroidal anti-inflammatory drops in preventing macular edema. Patient undergoing uncomplicated cataract surgery will be enrolled and randomized to nepafenac, ketorolac, or placebo. Follow-up will occur at 1 month with ocular coherence tomography (OCT).

NCT ID: NCT01385852 Completed - Clinical trials for Cystoid Macular Edema Following Cataract Surgery

CME With Different Fluidic Parameters

Start date: May 2010
Phase: Phase 4
Study type: Interventional

Understanding and modulating fluid parameters is an important, but often overlooked aspect of phacoemulsification. In a previous study we compared the impact of using high fluid parameters versus low fluidic parameters on real-time IOP measured during phacoemulsification. The investigators found that using high parameters resulted in a higher absolute rise in IOP as well as higher fluctuations in the IOP when compared to low parameters. Clinically these higher fluctuations in IOP would translate in a higher chamber instability. Based on the results of this study, the investigators decided to take it further and study the impact of using high parameters (and thus, higher chamber instability) on macular edema and thickness following surgery, in an otherwise uncomplicated surgery. Higher fluid parameters during phacoemulsification predisposes the eye to increased macular thickness

NCT ID: NCT01376362 Completed - Uveitis Clinical Trials

Topical Interferon Gamma for Macular Edema Secondary to Uveitis

JakStat2
Start date: June 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of this study is to investigate the safety and efficacy of ocular instillations of interferon gamma-1b as a potential treatment for cystoid macular edema (CME) secondary to uveitis.

NCT ID: NCT01363440 Completed - Clinical trials for Diabetic Macular Edema

Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Patients With Diabetic Macular Edema

VISTA DME
Start date: May 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) on the best corrected visual acuity (BCVA) assessed by the early treatment diabetic retinopathy study (ETDRS) chart in patients with diabetic macular edema (DME) with central involvement.

NCT ID: NCT01358396 Completed - Clinical trials for Diabetic Macular Edema

Glycemic Control and Diabetic Macular Edema

Start date: January 2010
Phase: Phase 1
Study type: Observational

Does diabetic patients' glycemic control affect their response to laser and/or intravitreal injection therapy in terms of visual and anatomical outcomes.