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Clinical Trial Summary

Clinical and genetic evaluation of individuals treated with intravitreal aflibercept injection (Eylea) for neovascular age-related macular degeneration (wet AMD)


Clinical Trial Description

Clinical and genetic assessment of treatment response in patients with age-related macular degeneration using intravitreal aflibercept injection. This study seeks to determine if different genetic polymorphisms of vascular endothelial growth factor A (VEGF-A) and HtrA serine peptidase 1(HTRA1) and other genes correlate to the response to intravitreal aflibercept injection therapy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02689518
Study type Interventional
Source University of California, San Diego
Contact
Status Completed
Phase Phase 4
Start date April 2014
Completion date November 12, 2019

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