Weight in Lower Limbs Improves Gait Ataxia of in Machado-Joseph Disease Patients

Machado-Joseph Disease Clinical Trial

Official title: Weight in Lower Limbs Improves Gait Ataxia Of in Machado-Joseph Disease Patients: A Randomized Crossover Trial

Status Completed

Clinical Trial Summary

Few studies evaluated the efficacy of adding weights on the lower limbs in patients with ataxic disorders. There is no current evidence on which would be the most appropriate weight for use in this context. To assess progress and benefits of using this load, gait of symptomatic carriers of spinocerebellar ataxia type 3/Machado Joseph disease the objective of the study is to evaluate the gait with and without different load weights on lower limbs. Outcomes were the Scale for the Assessment and Ataxia Rating of (SARA), kinematic gait assessment by the accelerometer and gyroscope and the Patient Global Impression (PGI) about which weight they prefer for walking.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Gait Ataxia
• Machado-Joseph Disease

• NCT number: NCT02906046
• Study type: Interventional
• Source: Federal University of Health Science of Porto Alegre
• Status: Completed
• Phase: N/A
• Start date: April 2012
• Completion date: July 2014