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Clinical Trial Summary

To learn more about the usefulness of molecular testing with the Molecular Functional (MF) Portrait (a commercial test conducted by the sponsor of this study, BostonGene) in guiding lymphoma care.


Clinical Trial Description

Primary Objective: • To determine the feasibility and turnaround of clinical WES and transcriptome sequencing Secondary Objectives: - To determine the frequency of actionable DNA and RNA alterations - To determine the concordance of DNA and RNA alterations - To determine the frequency of molecularly matched therapy - To determine the feasibility of identifying mechanism(s) of acquired resistance with genomic profiling - To determine the feasibility of molecularly matched therapy to acquired resistance alterations Exploratory Objectives: - To determine the feasibility of prioritizing targets with precision analytics - To determine clinical outcomes in patients receiving molecularly matched therapy - To determine the role of additional emerging diagnostic technologies ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05464823
Study type Interventional
Source M.D. Anderson Cancer Center
Contact Jason Westin, MD
Phone (713) 792-3750
Email jwestin@mdanderson.org
Status Recruiting
Phase N/A
Start date July 7, 2022
Completion date May 12, 2027

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