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Lymphoma clinical trials

View clinical trials related to Lymphoma.

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NCT ID: NCT05940272 Recruiting - Lymphoma Clinical Trials

Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers

Start date: July 3, 2023
Phase:
Study type: Observational

The purpose of this study is to develop and test a new communication training intervention called Hematolo-GIST to help oncologists communicate with patients about their lymphoma diagnosis and advance care planning.

NCT ID: NCT05940064 Recruiting - Clinical trials for Diffuse Large B Cell Lymphoma

Prospective Clinical Study of ZPR Regimen in Elderly Treatment-naive Diffuse Large B-cell Lymphoma

Start date: July 20, 2023
Phase: Phase 2
Study type: Interventional

This is a prospective, single-arm, single-center clinical study. This clinical study aims to explore the efficacy and safety of the ZPR(Zanubrutinib, Polatuzumab vedotin and Rituximab)regimen in elderly patients with treatment-naive diffuse large B-cell lymphoma.

NCT ID: NCT05940051 Recruiting - Clinical trials for Diffuse Large B Cell Lymphoma

Prospective Clinical Study of ZPR Regimen in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Start date: July 20, 2023
Phase: Phase 2
Study type: Interventional

This is a prospective, single-arm, single-center clinical study. This clinical study aims to explore the efficacy and safety of the ZPR(Zanubrutinib, Polatuzumab vedotin and Rituximab)regimen in the treatment of patients with relapsed and refractory diffuse large B-cell lymphoma.

NCT ID: NCT05938127 Recruiting - Hodgkin Lymphoma Clinical Trials

Impact of Respiratory Training in Lymphoma Survivors

Start date: December 2024
Phase: N/A
Study type: Interventional

High-resistance inspiratory muscle strength training (IMST) is a time-efficient (~5 minutes/day) form of exercise that employs an affordable, handheld device which impedes inspiratory breathing to train the diaphragm and accessory respiratory muscles and has demonstrated improvements in both cardiovascular health (9 mmHg reduction in systolic blood pressure, 45% improvement in vascular endothelial function) and improve exercise tolerance (12% increase in treadmill exercise time) in generally healthy midlife/older adults. Therefore, this approach may circumvent preventative hurdles to exercise, and augment the effects of exercise for capable survivors.

NCT ID: NCT05934864 Recruiting - Clinical trials for Peripheral T Cell Lymphoma

Different Molecular Subtypes of Peripheral T-cell Lymphoma, a Real-world Registry Study. (TRUST)

Start date: July 13, 2023
Phase:
Study type: Observational [Patient Registry]

A multi-center, prospective, registry study to analyze the clinical characteristics and prognosis of different molecular subtypes of peripheral T-cell lymphoma.

NCT ID: NCT05934838 Recruiting - Clinical trials for Mantle Cell Lymphoma

A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell Lymphomas

Start date: October 4, 2023
Phase: Phase 1
Study type: Interventional

This is a clinical trial to evaluate the feasibility and safety of giving tazemetostat followed by standard of care CAR T cell infusion in previously treated diffuse large b-cell lymphoma (DLBCL), follicular lymphoma (FL), and mantle cell lymphoma (MCL). The investigators hypothesis is that this combination has the potential to significantly improve the ability of CART cells to recognize and kill lymphoma cells without a significant impact on safety. Participants will receive the tazemetostat pills before and after receiving their CAR T cell therapy, for up to 12 months after CAR T cell administration. Patients will be followed for up to 5 years.

NCT ID: NCT05934513 Recruiting - Clinical trials for Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

A Study of GFH009 Monotherapy in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

Start date: September 6, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is a multicentre, open-label phase Ib/II study. The purpose of the study is to assess the efficacy, safety/ tolerability and pharmacokinetic of GFH009 monotherapy in patients with relapsed or refractory peripheral T-cell lymphoma

NCT ID: NCT05934448 Recruiting - Clinical trials for Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

Start date: November 15, 2023
Phase: Phase 2
Study type: Interventional

This research study is evaluating the combination of drugs, pembrolizumab with chimeric antigen receptor (CAR) T-cell therapy, as a possible treatment for primary mediastinal B-cell lymphoma that has recurred after prior treatment. The names of the study drugs involved in this study are: - Pembrolizumab Standard treatment will include: - CAR T-cell therapy (either axicabtagene-ciloleucel or lisocabtagene maraleucel) - Cyclophosphamide - Fludarabine

NCT ID: NCT05931328 Recruiting - Clinical trials for Relapsed or Refractory (R/R) Primary Central Nervous System Lymphoma

The Study of the Combination of Thiotepa and Pomalidomide for the Treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma Patients.

Start date: October 15, 2022
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of the combination of thiotepa and pomalidomide in the treatment of relapsed/refractory (R/R) primary central nervous system lymphoma (PCNSL).

NCT ID: NCT05929612 Recruiting - Lymphoma Clinical Trials

A Study of Response Adapted Ultra Low Dose 4 Gy Radiation for Definitive Therapy of Marginal Zone Lymphoma

Start date: July 28, 2023
Phase: Phase 2
Study type: Interventional

To learn if response-adapted, ultra-low dose radiation therapy can help to control MZL. This means participates first receive lower does of radiation therapy and then, based on how the disease responds, may receive higher doses after that.