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Clinical Trial Summary

This study wil examine the effect of altered intrathoracic pressure on lymphatic function, by investigating the lymphatic vessels in the lower limb during mechanical ventilation. The lymphatic function will be examined using Near-Infrared Fluorescence Imaging.


Clinical Trial Description

This study wil examine the effect of altered intrathoracic pressure on lymphatic function. This will be done by investigating peripheral lymphatic vessels on patients undergoing surgery for malformations of the jaw who are being mechanically ventilated. Subjects will be examined on two occasions. One to establish baseline function, and one during surgery following a ventilation protocol with altered PIP and PEEP. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05770752
Study type Interventional
Source Rigshospitalet, Denmark
Contact Lene Thorup, MD
Phone +4535457845
Email lene.thorup.01@regionh.dk
Status Recruiting
Phase N/A
Start date February 1, 2023
Completion date October 2024

See also
  Status Clinical Trial Phase
Completed NCT04595448 - Lymphatic Function in Patients With Secondary Tricuspid Valve Regurgitation