Lymph Node Metastases Clinical Trial
Official title:
Central Cervical Dissection for Clinical Node Negative Papillary Thyroid Carcinoma: a Prospective Study
This study is divided into three stages. In the first stage, the investigators try to explore
the objective clinical imaging standard of cN0PTC on the basis of previous studies, formulate
the "clinical imaging standard of cN0PTC", and randomly enroll 2000 patients under the
premise of meeting the standard to establish the "predictive model of cN0-pN+PTC".
In the second stage, 2000 patients will be enrolled to test and improve the evaluation
efficiency of "cN0-pN+PTC prediction model".
In the third stage, 2 000 patients without lymph node metastasis assessed by "cNo-pN+ PTC
prediction model" will be randomly divided into experimental group and control group. The
experimental group will be treated with pCND, while the experimental group will be treated
without pCND. The central lymph node metastasis probability, the number and size of
metastatic lymph nodes in the control group will be observed after operation. The two groups
will be followed up for 5, 10, 15 and 20 years to observe the RFS and OS, so as to further
evaluate the "cN0-pN+PTC prediction model" scientifically.
n/a
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