Lymph Node Metastases and Arterial Ligation in Rectal Cancer Surgery

Lymph Node Metastases Clinical Trial

Official title:

Localisation of Mesenteric Lymph Node Metastases and Role of Level of Arterial Ligation in Rectal Cancer Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03314961
• Other study ID #: Dnr2013/099
• Status: Completed
• Phase: N/A
• First received: October 16, 2017
• Last updated: October 16, 2017
• Start date: January 2012
• Est. completion date: December 2016

Study information

• Verified date: October 2017
• Source: Landstinget Västmanland
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Lymph node status is of major prognostic importance in non-metastatic rectal cancer. For oncological reasons, central arterial ligation of the inferior mesenteric artery (IMA) is suggested. However, there is no conclusive evidence presented for this procedure.

This study aimed at investigating the localisation of lymph node metastases and the role of central versus peripheral arterial ligation of in rectal cancer specimens.

Description:

Prospective population-based study of specimens from patients that underwent surgical resection for rectal cancer in Västmanland County, Sweden. Specimens were divided in 3 sections (A-C) and the total amount of lymph nodes and the location of lymph node metastases were analysed.

Multivariate analysis was used to explore the relationship between lymph node counts and age, gender, BMI, preoperative oncological treatment, type of surgery, tumour stage, vessel and specimen length.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 151
• Est. completion date: December 2016
• Est. primary completion date: December 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• All patients that were curatively operated for rectal cancer in Västmanlands county 2012-2016.

Exclusion Criteria:

• Patients that were not operated or had another type of cancer.

Related Conditions & MeSH terms

• Lymph Node Metastases
• Neoplasm Metastasis
• Rectal Neoplasms

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Landstinget Västmanland

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Lymph node metastases in rectal cancer	Analyses of number and location of lymph node metastases in rectal cancer	2012-2016