Lung Ultrasound Clinical Trial
Official title:
Lung Ultrasound-guided Hemodynamic Optimization in Major Non-cardiac Surgery: a Randomized Control
The formalized expert recommendation of the French Society of Anesthesia and Intensive Care recommends guiding vascular filling by measuring the stroke volume (SV) in surgical patients considered at high risk. Vascular filling should be continued in the event of preload dependence and stopped in the event of the appearance of preload independence. The aim is to avoid vascular overload due to excessive vascular filling. The application of this recommendation has resulted in a reduction in postoperative morbidity, length of hospital stay and time to return to oral feeding. The superiority of this strategy is now being questioned and the predictive indices of response to vascular filling (static and dynamic) have many limitations. In addition, none of the cardiac output monitors are the gold standard for intraoperative use. Through the study of artefacts, lung ultrasound has been gaining ground over the last twenty years, particularly in cardiology, nephrology and intensive care. By analogy with radiological B-lines, ultrasound B-lines result from the reverberation of ultrasound on the subpleural inter-lobular septa thickened by oedema. The Fluid Administration Limited by Lung Sonography (FALLS) protocol, described by Lichtenstein et al, is defined as the visualisation of new B lines during a vascular filling test. If a B-line appears in an area where it was not present during vascular filling, the most likely diagnosis is hydrostatic overload of the subpleural interstitial septum. This appearance of B-lines occurs at a sub-clinical stage. The use of lung ultrasound could allow real-time assessment of vascular filling and its tolerance during the intraoperative period. The main objective of the study is to demonstrate a decrease in the incidence of postoperative complications (organ failure) (as defined by international guidelines) when using lung ultrasound-guided haemodynamic optimisation compared to standard optimisation.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT04057625 -
Transthoracic Ultrasound in the Diagnosis and Follow-up of Ventilator Associated Pneumonia
|
N/A | |
Terminated |
NCT02556853 -
Ultrasound for Double Lumen Endotracheal Tube
|
N/A | |
Active, not recruiting |
NCT03546699 -
Hospital-wide Incidence, Clinical Characteristics and Outcomes of ARDS
|
||
Recruiting |
NCT03619525 -
Ultrasonographic Assessment of the Effect of CPB Acute Lung Injury
|
N/A | |
Completed |
NCT05132036 -
Lung Ultrasound Assessment of Fluid Overload in Haemodialysis Patients
|
N/A | |
Not yet recruiting |
NCT04618627 -
Role of Lung Ultrasonography in Prediction of the Seveity and the Need for Surfactant Administration in Neonates With Respiratory Distress Syndrome
|
||
Completed |
NCT04474236 -
Lung Ultrasound for COVID-19 Initial Triage and Monitoring
|
||
Active, not recruiting |
NCT05035459 -
B-lines-guided Heart Failure Management in Heart Failure Patients
|
||
Not yet recruiting |
NCT05272982 -
Thoracic Fluid Content by Electrical Cardiometry Versus Lung Ultrasound in Mechanically Ventilated Patients
|
||
Not yet recruiting |
NCT06235645 -
dEtection of rheumAtoid aRthritis - Interstitial Lung dIseasE by Thoracic ultRasound
|
||
Not yet recruiting |
NCT05261295 -
Comparison of PEEP Effect on Perioperative Oxygenation and Postoperative Pulmonary Complications in Lithotomy Position
|
||
Recruiting |
NCT06430229 -
Atelectasis Frequency in Different Ventilation Modes
|
N/A | |
Completed |
NCT04719234 -
Lung Ultrasonography in COVID-19 Pneumonia
|
N/A | |
Not yet recruiting |
NCT06443528 -
Comparison of Lung Ultrasound Scores With Clinical Models for Predicting Bronchopulmonary Dysplasia:A Multi-center Prospective Cohort Study
|
||
Recruiting |
NCT05024942 -
LUS in Aortic Stenosis Patients Undergoing TAVR
|
||
Completed |
NCT05706441 -
Lung and Diaphragm Ultrasound Evaluation During Weaning From Mechanical Ventilation in COVID-19 Patients
|
||
Recruiting |
NCT05175313 -
Transthoracic Ultrasonography Findings and Their Relation to Spirometric Indices in Patients With Obstructive and Restrictive Respiratory Diseases
|
||
Completed |
NCT04805684 -
Different Lung Ultrasound Imaging Protocols in COVID-19 Pneumonia
|
N/A | |
Recruiting |
NCT06157138 -
Observation of B-lines in Pulmonary Echography, During Open Abdominal Surgery
|
||
Completed |
NCT05171608 -
Preoperative Ultrasound-based Protocol for Optimization of Fluid Therapy to Prevent Early Intraoperative Hypotension
|
N/A |