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Lung Clearance Index and Lung Allograft Dysfunction

Lung Transplantation Clinical Trial

Official title:
Lung Clearance Index for the Early Detection and Monitoring of Lung Allograft Dysfunction After Adult Lung Transplantation

Clinical Trial Summary

The aim of this project is to evaluate the ability of the lung clearance index (LCI) to detect early chronic lung allograft failure (CLAD) in adult lung transplant recipients over a period of 3 years.

Clinical Trial Description

This single center study consists of three parts:

1. Characterisation of the Zurich lung transplant cohort regarding CLAD status and pulmonary function impairment (cross-sectional, study part I)

2. Evaluation of test-retest reliability of LCI in 20 clinically stable lung transplant recipients during three consecutive study visits (study part II)

3. Prospective cohort study to test the ability of LCI to detect early CLAD in patients without prior CLAD (study part III) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03850002
Study type Observational
Source University of Zurich
Contact
Status Withdrawn
Phase
Start date March 1, 2019
Completion date September 30, 2023
View Details
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