OCS Lung System EXPAND II Trial

Status Terminated

Clinical Trial Summary

To evaluate the safety and effectiveness of the OCS™ Lung System to recruit, preserve and assess non-ideal donor lungs that may not meet current standard donor lung acceptance criteria for transplantation.

Clinical Trial Description

Inclusion At least one of the following: - Donor PaO2/FiO2 ≤ 300 mmHg at the time of the offer; or - Expected cross-clamp time > 6 hours for the second lung; or - Donor after Cardiac Death (DCD donor); or - Donor age ≥ 55 years old ;

Study Design

Related Conditions & MeSH terms

Lung Transplantation

Clinical Trial Details

NCT number	NCT03343535
Study type	Interventional
Source	TransMedics
Contact
Status	Terminated
Phase	N/A
Start date	March 12, 2018
Completion date	July 6, 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02581111` - Naloxone for Optimizing Hypoxemia Of Lung Donors	Phase 2/Phase 3
Recruiting	`NCT02177916` - Patient Education Study to Determine Knowledge Acquisition in Patients Preparing to Undergo Lung Transplantation	N/A
Not yet recruiting	`NCT01394835` - Safety and Efficacy of Inhaled Alpha-1 Antitrypsin in Preventing Bronchiolitis Obliterable Syndrome in Lung Transplant Recipients	Phase 2
Completed	`NCT01204970` - Confocal Laser Micro-endoscopy in Chronic Obstructive Pulmonary Disease (COPD) and Lung Transplant Recipients	N/A
Not yet recruiting	`NCT01162148` - Pulmonary Rehabilitation and Inspiratory Muscle Training (IMT) for Patients Following Lung Transplantation	N/A
Active, not recruiting	`NCT00980967` - Predictive Factors for Chronic Rejection in Lung Transplant Recipients: COLT Study	N/A
Completed	`NCT00531921` - Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival	N/A
Recruiting	`NCT00163696` - Multi Breath Nitrogen Washout (MBNW) as a Measure of Small Airway Function in Patients With Respiratory Disease	N/A
Completed	`NCT00177684` - Pharmacokinetic Profiles of Inhaled Lipid Complex Amphotericin B (Abelcet ®)	Phase 3
Completed	`NCT00163891` - Comparison of Two Chest Physiotherapy Protocols in Lung Transplant Recipients	N/A
Completed	`NCT03668483` - Relation Between Muscle Strength With Exercise Capacity and Dyspnea in LTx	N/A
Not yet recruiting	`NCT02855372` - Impact of the Age Difference Between the Donor and Recipient on the Morbidity and Mortality After Lung Transplantation. Study on a National Multicenter Cohort (COLT)	N/A
Completed	`NCT01211509` - Montelukast in Bronchiolitis Obliterans Syndrome	Phase 4
Completed	`NCT01212406` - Vitamin D in Bronchiolitis Obliterans Syndrome	Phase 4
Not yet recruiting	`NCT00808600` - Empowerment of Lung and Heart-lung Transplant Patients	N/A
Completed	`NCT00553397` - Live Lung Donor Retrospective Study	N/A
Completed	`NCT00402805` - Improving the Humoral Response to Influenza Vaccine in Lung Transplant Recipients by an Intradermal Strategy	Phase 4
Completed	`NCT00701922` - Surveillance Study of Viral Infections Following Lung Transplantation	N/A
Terminated	`NCT00235651` - Abelcet Radiotagging Protocol: Inhaled Lipid Complex Abelcet® in Lung Transplant Recipients	Phase 3
Active, not recruiting	`NCT02936505` - Clinical Study Evaluating Two Treatment Protocols for Immunosuppressive Drugs. Looking at 3-year Incidence of CLAD.	N/A