Lung Transplantation Clinical Trial
Official title:
Pulmonary Rehabilitation and Inspiratory Muscle Training (IMT) for Patients Following Lung Transplantation
Lung transplantation (LT) is now an established treatment option for patients with a wide
variety of end-stage lung diseases- aims to improve quality of life and survival. Pulmonary
rehabilitation (PR) is widely recognized as an important component of care of patients with
chronic obstructive pulmonary disease (COPD), it improves dyspnea, exercise tolerance,
quality of life, and reduces healthcare resource utilization.
The goal of pulmonary rehabilitation following lung transplantation is to enhance the
physiological and functional benefits resulting from surgery. Inspiratory muscle Training
(IMT) is defined as any intervention with the goal of training the inspiratory muscles. IMT
can improve inspiratory muscles strength, endurance and exercise capacity in adults with
COPD. IMT provides additional benefits to patients undergoing PR program and is worthwhile
even in patients who have already undergone a general exercise reconditioning (GER) program.
IMT will provide additional benefits (together or without) PR to patients following lung
transplantation. No formal guidelines exist regarding the optimal methods of exercise
training component of pulmonary rehabilitation for patients recovering from lung
transplantation. This study will evaluate the unique influence of IMT in Patients Following
Lung Transplantation.
Status | Not yet recruiting |
Enrollment | 50 |
Est. completion date | September 2011 |
Est. primary completion date | December 2010 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - Post lung transplant patients attending the pulmonary Institute , will be invited to participate,They will be co-operative and able to perform spirometry; and other lung tests. - Patients will be stable clinically,for at least one month,the patients will be all new to an IMT program. Exclusion Criteria: - Patients with cardiac disease,poor compliance,or requirement of supplemental oxygen. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Supportive Care
Country | Name | City | State |
---|---|---|---|
Israel | Pulmonary Institute Rabin Medical center, Beilinson Hospital | Petach Tikva |
Lead Sponsor | Collaborator |
---|---|
Rabin Medical Center |
Israel,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | maximal exercise capacity | at 9 months after starting interventions | 9 months after starting interventions | No |
Secondary | Lung function (FEV1, FVC) | 9 months after starting interventions | 9 months after starting interventions | No |
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