Lung Transplantation Clinical Trial
Official title:
Pulmonary Rehabilitation and Inspiratory Muscle Training (IMT) for Patients Following Lung Transplantation
Lung transplantation (LT) is now an established treatment option for patients with a wide
variety of end-stage lung diseases- aims to improve quality of life and survival. Pulmonary
rehabilitation (PR) is widely recognized as an important component of care of patients with
chronic obstructive pulmonary disease (COPD), it improves dyspnea, exercise tolerance,
quality of life, and reduces healthcare resource utilization.
The goal of pulmonary rehabilitation following lung transplantation is to enhance the
physiological and functional benefits resulting from surgery. Inspiratory muscle Training
(IMT) is defined as any intervention with the goal of training the inspiratory muscles. IMT
can improve inspiratory muscles strength, endurance and exercise capacity in adults with
COPD. IMT provides additional benefits to patients undergoing PR program and is worthwhile
even in patients who have already undergone a general exercise reconditioning (GER) program.
IMT will provide additional benefits (together or without) PR to patients following lung
transplantation. No formal guidelines exist regarding the optimal methods of exercise
training component of pulmonary rehabilitation for patients recovering from lung
transplantation. This study will evaluate the unique influence of IMT in Patients Following
Lung Transplantation.
The post lung transplant patients will participate in a rehabilitation program for 6 months.
Participants in the proposed study will belong to one of four intervention groups:
1. Conventional or regular pulmonary rehabilitation program alone(an exercise program that
consist 3 main components: aerobic conditioning, resistance training, and flexibility
exercises).
2. Very low load IMT(sham IMT) alone.
3. Conventional or regular pulmonary rehabilitation program + Targeted inspiratory
resistive or threshold IMT.
4. Targeted inspiratory resistive or threshold IMT alone.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Supportive Care
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