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Lung Neoplasms clinical trials

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NCT ID: NCT01131234 Completed - Clinical trials for Stage IV Breast Cancer

Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors

Start date: May 2010
Phase: Phase 1
Study type: Interventional

This phase I clinical trial is studying the side effects and best dose of giving gamma-secretase inhibitor RO4929097 and cediranib maleate together in treating patients with advanced solid tumors. Gamma-secretase inhibitor RO4929097 and cediranib maleate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Cediranib maleate also may stop the growth of tumor cells by blocking blood flow to the tumor.

NCT ID: NCT01130961 Completed - Lung Cancer Clinical Trials

Management of Advanced Non-Small Cell Lung Cancer (NSCLC) and Clinical Outcomes in Patients Who Received Gefitinib in Thailand

Start date: October 2009
Phase: N/A
Study type: Observational

The purpose of this study is to determine progression-free survival of lung cancer patients who received gefitinib in clinical practice in Thailand.

NCT ID: NCT01130779 Enrolling by invitation - Clinical trials for Non-small Cell Lung Cancer

The Continuation of Erlotinib

Start date: August 2009
Phase: Phase 2
Study type: Interventional

Newly developed or progressive brain metastasis during erlotinib treatment is considered progressive disease requiring change of treatment regimens despite no progression in extracranial lesions. Given that there is a dissociation in terms of response to erlotinib between brain and extracranial sites, we intend to conduct this pilot study to determine whether the continuation of erlotinib treatment can prolong the progression free interval of extracranial lesions as long as cranial lesion is controlled separately by conventional treatment modalities such as surgical resection, stereotactic radiosurgery, and whole brain radiotherapy.

NCT ID: NCT01130766 Enrolling by invitation - Clinical trials for Non-small Cell Lung Cancer

Asymptomatic Brain Metastasis in Non-small Cell Lung Cancer (NSCLC)

Start date: June 2008
Phase: Phase 3
Study type: Interventional

The prognosis of NSCLC patients with asymptomatic brain metastasis, who are not treated with SRS or WBRT has not been fully investigated yet. This randomized phase III trial is conducted to determine the exact role of SRS in NSCLC patients with asymptomatic oligo brain metastases whether early treatment with SRS would improve survival even in patients with asymptomatic brain metastasis.

NCT ID: NCT01130753 Completed - Lung Neoplasms Clinical Trials

Efficacy of Erlotinib in Neoadjuvant Setting in Patients With Stage IIIA, N2-positive Non-Small Cell Lung Cancer

Start date: January 2007
Phase: Phase 2
Study type: Interventional

This study propose neoadjuvant chemotherapeutic role by erlotinib.

NCT ID: NCT01130714 Completed - Lung Cancer Clinical Trials

Resistance Training in Lung Cancer Patients on Chemotherapy

Start date: January 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effectiveness of a resistance training program on reducing systemic inflammation and improving chemotherapy completion in lung cancer patients being treated with curative intent chemotherapy.

NCT ID: NCT01130285 Active, not recruiting - Lung Cancer Clinical Trials

Validation of a Multi-gene Test for Lung Cancer Risk

Start date: May 2011
Phase:
Study type: Observational

The purpose of this study is to determine the validity of a multi-gene Lung Cancer Risk Test (LCRT). In the process, the investigators will establish a bank of NBEC samples and corresponding blood samples from individuals demographically at increased risk for lung cancer.

NCT ID: NCT01126736 Completed - Clinical trials for Non Small Cell Lung Cancer

Eribulin Mesylate Administered in Combination With Pemetrexed Versus Pemetrexed Alone as Second Line Therapy in Patients With Stage IIIB or IV Nonsquamous Non Small Cell Lung Cancer

Start date: June 10, 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether Eribulin Mesylate Administered in Combination with Pemetrexed is safe and tolerable and to gain a preliminary indication of clinical benefit when administered to Patients with Stage IIIB or IV Nonsquamous Non Small Cell Lung Cancer.

NCT ID: NCT01126346 Completed - Clinical trials for Unspecified Childhood Solid Tumor, Protocol Specific

Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

HOPE
Start date: May 2010
Phase: N/A
Study type: Interventional

RATIONALE: An orientation and patient education program and telephone counseling may help improve the quality of life in patients with peritoneal surface malignancies. PURPOSE: This clinical trial studies quality of life and survivorship care in patients undergoing surgery and chemotherapy for peritoneal surface malignancies.

NCT ID: NCT01125995 Completed - Clinical trials for Small Cell Lung Cancer

Early Versus Late Concurrent Chemoradiation for Limited Stage Small-cell Lung Cancer

Start date: June 2003
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy and toxicity of different timing of concurrent chemoradiation in the treatment of limited disease status Small-cell lung cancer.