Lung Cancer Clinical Trial
Official title:
Retrospective Research on Lung Cancer Patients Receiving Neoadjuvant Immunochemotherapy From Zhongshan Hospital Fudan University.
NCT number | NCT06023797 |
Other study ID # | ZS-chest |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | January 2017 |
Est. completion date | July 2023 |
Verified date | September 2023 |
Source | Shanghai Zhongshan Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
We retrospectively analyzed lung cancer patients who had NAICT and surgery in the Department of Thoracic Surgery, Zhongshan Hospital. NAICT was defined as chemotherapy that included at one application of PD-1 inhibitor.
Status | Completed |
Enrollment | 83 |
Est. completion date | July 2023 |
Est. primary completion date | November 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: 1. Lung surgery was performed in the Department of Thoracic Surgery at Zhongshan Hospital; 2. At least one cycle of neoadjuvant treatment containing the immune drug PD-1 immunosuppressant was performed before surgery; 3. Malignancy was present and confirmed in the pathology before treatment and after surgery; 4. The lung lesion was the primary lesion. Exclusion Criteria: 1. No lung surgery was performed until 2022.11; 2. No preoperative neoadjuvant therapy was performed or recorded; 3. Neoadjuvant therapy did not include immune drugs; 4. Previous history of malignancy (including surgery and adjuvant therapy); 5. Previous use of system-related immune medicines, such as immunosuppressants and monoclonal antibodies; and 6. Other conditions inappropriate for enrollment by the investigator. |
Country | Name | City | State |
---|---|---|---|
China | Zhencong Chen | Shanghai | Shanghai |
Lead Sponsor | Collaborator |
---|---|
Shanghai Zhongshan Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Progression-free survival (PFS) | Progression-free defined as status of recurrence of lung cancer | 2017-2023 | |
Primary | Overall survival (OS) | Overall defined as the living status, alive or dead | 2017-2023 |
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