Lung Cancer Clinical Trial
— Vortex_USOfficial title:
From Benchmark to Surgical Activity: the Role of Endobronchial Fiducial Markers for Ground Glass Lung Nodules Resection.
With the risen popularity of low-dose computed tomography (LDCT) for lung cancer screening, many patients present with peripheral pulmonary ground-glass nodules (GGNs) with a suspicious solid part. The appropriate diagnostic and management strategy for those lesions can be questionable. If malignancy is suspected, a surgical biopsy with the guidance of various localization methods available is recommended. Each localization method has its advantages and disadvantages. Therefore, it may not be possible to establish a gold standard for localizing indeterminate lung nodules since comparative clinical trials are lacking.
Status | Recruiting |
Enrollment | 5 |
Est. completion date | September 30, 2024 |
Est. primary completion date | September 30, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - all patients over the age of 18; - lung GGNs with the presence of a solid part inside > = 6 mm or with a solid part even less than 6 mm but with an increase in size; - subjects evaluated for surgical treatment during multidisciplinary tumor board. Exclusion Criteria: - Patients not eligible for surgery |
Country | Name | City | State |
---|---|---|---|
Italy | Gian Piero Bandelli | Bologna | Emilia Romagna |
Lead Sponsor | Collaborator |
---|---|
IRCCS Azienda Ospedaliero-Universitaria di Bologna |
Italy,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Rate of adverse events | Rate of complications due to endobronchial positioning of fiducial markers under augmented fluoroscopy to mark ground glass opacities. | 12 months | |
Secondary | Number of fiducial markers completely removed | Number of fiducial markers placed under augmented fluoroscopy completely removed (margins free from disease) after surgical removal of ground glass opacities in the lung | 12 months |
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