Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

This is an open-label, non-randomized, single-center, phase II study to evaluate the efficacy, toxicity and, tolerability of pre-specified dose attenuated chemotherapy regimens in lung cancer patients with comorbidities. The investigator will indicate the rationale(s) for dose modification based on the subgroups of patients listed in the protocol. Patients may fit into multiple subgroups and this is accounted for in the prospectively defined dose reduction level as listed in the protocol. Prespecified doses by chemotherapeutic agent and dose level adjustment based on patient characteristics and comorbidities are listed in the protocol. Analyses will be stratified by treatment group 1-3 based on the treating physician's selected therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05800587
Study type	Interventional
Source	Fox Chase Cancer Center
Contact	Ryan Romasko
Phone	2678388380
Email	ryan.romasko@fccc.edu
Status	Recruiting
Phase	Phase 2
Start date	February 22, 2023
Completion date	August 1, 2029

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