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Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

Lung Cancer Clinical Trial

Official title:
A Phase II Trial of Durvalumab and Ablative Radiation in Extensive-Stage Small Cell Lung Cancer (DARES)

Clinical Trial Summary

This this study is for individuals who have treatment-naïve extensive-stage small cell lung cancer (small cell lung cancer that wont respond to treatment). Doctors leading this study hope to learn if combining durvalumab, carboplatin and etoposide with hyofractionated ablative radiation therapy (radiation focused on certain parts of the body) will help treat your cancer and improve how long you can live with extensive-stage small cell cancer without it getting worse (progression-free survival). Your participation in this research will last about 48 months. Durvalumab along with chemotherapy has been approved by the Food and Drug Administration (FDA) for the treatment of small cell lung cancer along with chemotherapy. This study is testing the addition of radiation to durvalumab and chemotherapy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05068232
Study type Interventional
Source University of Chicago
Contact Cancer Clinical Trials Office
Phone 1-855-702-8222
Email cancerclinicaltrials@bsd.uchicago.edu
Status Recruiting
Phase Phase 2
Start date August 19, 2022
Completion date October 1, 2027
View Details
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