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Clinical Trial Summary

This is a two arm, randomized, phase II study of patients with advanced KRAS mutation positive and PD-L1 high NSCLC who have not received therapy for advanced stage disease. Patients will be randomized between Arm A and Arm B treatment. Arm A treatment will consist of durvalumab every 4 weeks for 13 cycles. Arm B treatment will consist of durvalumab with chemotherapy every 3 weeks for 4 cycles followed by durvalumab with pemetrexed every 3 weeks for 13 cycles.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04470674
Study type Interventional
Source Hoosier Cancer Research Network
Contact
Status Withdrawn
Phase Phase 2
Start date April 6, 2021
Completion date June 8, 2021

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