Intervention of Engineered Immune Effector T Cells Against Lung Cancer

Status Withdrawn

Clinical Trial Summary

The primary objective of this study is to evaluate the safety of lung cancer specific cytotoxic lymphocytes (LC-CTLs). The secondary objectives are to evaluate the rate of successful LC-CTLs generation in vitro and determine the anti-lung cancer efficacy.

Clinical Trial Description

Lung cancer is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung. The two main types are small-cell lung carcinoma (SCLC) and non-small-cell lung carcinoma (NSCLC). Worldwide in 2012, lung cancer occurred in 1.8 million people and resulted in 1.6 million deaths. Common treatments include surgery, chemotherapy, and radiotherapy.

Adoptive immunotherapy with cytotoxic T lymphocytes (CTLs) reactive with specific viral antigens has proven to be effective. Here, the investigators aim to evaluate the safety and efficacy of multiple infusions of lung cancer specific cytotoxic T lymphocytes cells in patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03353428
Study type	Interventional
Source	Shenzhen Geno-Immune Medical Institute
Contact
Status	Withdrawn
Phase	Phase 1/Phase 2
Start date	November 15, 2017
Completion date	December 2020

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