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A Pilot Study to Develop Predictive Biomarkers for the Response to Immunotherapy in Lung Cancer

Lung Cancer Clinical Trial

Official title:
A Pilot Study to Develop Predictive Biomarkers for the Response to Immunotherapy in Lung Cancer

Clinical Trial Summary

Several immune checkpoint inhibitors targeting the PD-1 pathway have been developed with clinical trials showing an approximately 20% durable response in unselected patients with advanced non-small cell lung cancer (NSCLC). At the moment, no clear biomarker exists to accurately predict anti-PD1/PDL1 tumor responsiveness. The goal of this study is to broadly discover and evaluate the utility of blood based biomarkers for use in measuring and predicting response to immunotherapy in patients with lung cancer.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03047616
Study type Observational
Source Abramson Cancer Center of the University of Pennsylvania
Contact
Status Completed
Phase
Start date November 22, 2016
Completion date May 31, 2019
View Details
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