Lung Cancer Clinical Trial
Official title:
Evaluation of a Novel Molecular NSCLC Classification System
This research studies protein in tumor samples from patients with non-small cell lung cancer. Finding specific proteins in tumor tissue samples from patients with cancer may help doctors tell what type of lung cancer a patient has and plan better treatment.
PRIMARY OBJECTIVES:
I. To validate a novel 4-protein signature's ability to subtype non-small cell lung cancer
(NSCLC) in a treatment-naive, multi-institutional cohort, Cancer and Leukemia Group B (CALGB)
9761.
SECONDARY OBJECTIVES:
I. To estimate the NSCLC misclassification rate in a multi-institutional clinical-trial
setting for stage 1 NSCLC (adenocarcinoma versus squamous cell).
OUTLINE:
Previously collected tissue samples are analyzed via hematoxylin and eosin (H&E) staining and
immunohistochemistry (IHC).
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