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Clinical Trial Summary

RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

PURPOSE: This research trial studies tissue samples from patients with non-small cell lung cancer.


Clinical Trial Description

OBJECTIVES:

- To identify and characterize single nucleotide variations (SNVs) in non-small cell lung cancer (NSCLC) specimens.

- To identify and characterize structural variations in the genomes of NSCLC specimens.

- To identify and characterize other genomic alterations including, but not limited to, expression profiling and methylation.

OUTLINE: DNA and RNA extracted from archived specimens are analyzed for single nucleotide variations, structural variations in the genomes, and other genomic alterations including, but not limited to, gene expression profiling and methylation. Clinical data related to disease, treatment, and recurrence from each patient sample is also collected. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01414595
Study type Observational
Source Alliance for Clinical Trials in Oncology
Contact
Status Completed
Phase N/A
Start date March 2012

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