Lung Cancer Clinical Trial
Official title:
Measurement of Potential Biomarkers Predicting Erlotinib Response
RATIONALE: Studying samples of blood in the laboratory from patients receiving erlotinib
hydrochloride may help doctors learn more about the effects of erlotinib hydrochloride on
cells. It may also help doctors understand how well patients respond to treatment.
PURPOSE: This research study is studying biomarkers predicting response in patients with
non-small cell lung cancer previously treated with erlotinib hydrochloride.
OBJECTIVES:
- To evaluate whether serum NGAL, MMP-9, NGAL/MMP-9 complex, and soluble E-cadherin can
be utilized as biomarkers to predict response in patients with non-small cell lung
cancer treated with erlotinib hydrochloride.
OUTLINE: Serum samples are analyzed for NGAL, MMP-9, NGAL/MMP-9, and soluble E-cadherin by
ELISA and Luminex assays.
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