Vibration Response Imaging (VRI) in Patients Who Are Potential Candidates for Surgical Resection

Lung Cancer Clinical Trial

Official title: Vibration Response Imaging (VRI) in Patients Who Are Potential Candidates for Surgical Resection

Status Enrolling by invitation

Clinical Trial Summary

The primary purpose of the study is to investigate the use of VRI to guide the selection of patients for lung surgery. Perfusion scintigraphy is the current method to assess the fractional contribution of lung function of the remaining lung.

The hypothesis is that VRI can determine quantitative postoperative lung function equally accurately as a quantitative perfusion scan.

Clinical Trial Description

Primarily, VRI will be compared to perfusion (Q) scan by predicted post-operative (ppo) FEV1 and DLCO as predicted by VRI versus as predicted by Q scan. Secondary, the ppo as predicted by each test will be compared with the actual FEV1 and DLCO at 3 months post-operative; If these two methods provide similar results, VRI will be deemed an acceptable alternative to Q scan for determining patient selection for lung resection. Finally, the patient outcomes (30 day mortality and pulmonary complications) for those patients falling within guideline parameters using the VRI measurement will be analyzed to see if using VRI in clinical practice would indeed allow prediction of satisfactory results (similar to literature benchmarks). ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Lung Cancer

• NCT number: NCT00966511
• Study type: Observational
• Source: Deep Breeze
• Status: Enrolling by invitation
• Phase: N/A
• Start date: June 2009
• Completion date: December 2011