Lung Cancer Clinical Trial
Official title:
Transitoriness in Cancer Patients: a Cross-Sectional Study of Uncertainty, Locus of Control, Quality of Life and Existentials Views on Finality of Life in Cancer Patients
Transitoriness can be defined as confrontation with life's finitude. Cancer patients are perceived to experience this confrontation due to their diagnosis. It is perceived to impact cancer patients' ways of coping with the disease situation. In this study, cancer patients' levels of uncertainty, transitoriness and their perceived locus of control are assessed. It is aimed at exploring the association of uncertainty, locus of control, transitoriness and quality of life. If a stronger correlation of one or the other issue with quality of life can be discovered, it will inform the development of an adequate evidence-based nursing intervention to better support patients' coping with the disease.
Cancer is the second leading cause of death among individuals in the United States of
America (Ries et al., 2000). Gastro-intestinal (GI) cancers account for approximately
253,500 new cases each year in both men and women. Most of the patients with GI cancer have
a poor outcome (American Cancer Society., 2005; Ilson, 2001), accounting for approximately
16% of cancer related death in women and 25% of cancer related death in men (American Cancer
Society, 2005). Of all cancers, lung cancer is the leading cause for death among men and
women (American Cancer Society., 2005).
GI cancer constitutes a disease with intensive medical research focused on the improvement
of prevention, early detection and treatment. How patients with GI cancer deal with the
diagnosis remains understudied to date. Lung cancer research has focused particularly on
smoking and its impact on lung cancer epidemiology. Lung cancer patients' coping strategies
have been studied. Issues related to the meaning of life, health and self-care, physical
functioning, coping and support have been highlighted as being important in lung cancer
patients' dealing with their disease situation (Maliski, Sarna, Evangelista, & Padilla,
2003; Sharf, Stelljes, & Gordon, 2005). Similarly, patients' dealing with a diagnosis of
breast cancer has been investigated (Andritsch et al., 2004; Badger, Braden, Mishel, &
Longman, 2004; Northouse, Templin, Mood, & Oberst, 1998). Constructs such as uncertainty and
locus control are highly important in coping with the disease situation. Uncertainty has
been linked with quality of life (Sammarco, 2001;2003). Evidence also exists that
transitoriness, which is the confrontation with the finitude of human life, plays an
important role in how individuals cope (Cohen et al., 2004; Shaha & Cox, 2003). The
interrelationship between and among transitoriness, uncertainty and locus of control has yet
to be delineated. There is also a need to explore transitoriness more fully as it has mainly
been subsumed in concepts such as 'finding meaning in illness' or 'anxiety' (Houldin, 2003).
Transitoriness has been linked with patient outcomes such as quality of life (Houldin,
2003). It is necessary to explore the concept of transitoriness to establish its links with
uncertainty and locus of control. It is equally important to explore the association of
these three concepts together with patients' psycho-social well-being and quality of life.
By exploring these associations, the individual's way of coping with the cancer diagnosis
will be better understood and lead to the development of nursing interventions to support
persons with cancer, especially those with lung and GI cancer.
It will then be possible a) to explore the concept of transitoriness by describing its
interrelationship with uncertainty and locus of control, and b) to investigate the
association among transitoriness, uncertainty, locus of control, psycho-social well-being
and quality of life. The following research questions will be addressed in the study:
1. Is cancer patients' confrontation with life's finitude related to uncertainty and locus
of control?
2. Are cancer patients' confrontation with life's finitude, uncertainty and locus of
control associated with psychosocial well-being and quality of life?
3. Are there differences in these associations between patients with different forms of
cancer?
;
Time Perspective: Cross-Sectional
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03918538 -
A Series of Study in Testing Efficacy of Pulmonary Rehabilitation Interventions in Lung Cancer Survivors
|
N/A | |
Recruiting |
NCT05078918 -
Comprehensive Care Program for Their Return to Normal Life Among Lung Cancer Survivors
|
N/A | |
Active, not recruiting |
NCT04548830 -
Safety of Lung Cryobiopsy in People With Cancer
|
Phase 2 | |
Completed |
NCT04633850 -
Implementation of Adjuvants in Intercostal Nerve Blockades for Thoracoscopic Surgery in Pulmonary Cancer Patients
|
||
Recruiting |
NCT06006390 -
CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors
|
Phase 1/Phase 2 | |
Recruiting |
NCT06037954 -
A Study of Mental Health Care in People With Cancer
|
N/A | |
Recruiting |
NCT05583916 -
Same Day Discharge for Video-Assisted Thoracoscopic Surgery (VATS) Lung Surgery
|
N/A | |
Completed |
NCT00341939 -
Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data
|
||
Not yet recruiting |
NCT06376253 -
A Phase I Study of [177Lu]Lu-EVS459 in Patients With Ovarian and Lung Cancers
|
Phase 1 | |
Recruiting |
NCT05898594 -
Lung Cancer Screening in High-risk Black Women
|
N/A | |
Active, not recruiting |
NCT05060432 -
Study of EOS-448 With Standard of Care and/or Investigational Therapies in Participants With Advanced Solid Tumors
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT03575793 -
A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT03667716 -
COM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors.
|
Phase 1 | |
Terminated |
NCT01624090 -
Mithramycin for Lung, Esophagus, and Other Chest Cancers
|
Phase 2 | |
Terminated |
NCT03275688 -
NanoSpectrometer Biomarker Discovery and Confirmation Study
|
||
Not yet recruiting |
NCT04931420 -
Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels
|
Phase 2 | |
Recruiting |
NCT06052449 -
Assessing Social Determinants of Health to Increase Cancer Screening
|
N/A | |
Recruiting |
NCT06010862 -
Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors
|
Phase 1 | |
Not yet recruiting |
NCT06017271 -
Predictive Value of Epicardial Adipose Tissue for Pulmonary Embolism and Death in Patients With Lung Cancer
|
||
Recruiting |
NCT05787522 -
Efficacy and Safety of AI-assisted Radiotherapy Contouring Software for Thoracic Organs at Risk
|